Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg

Ekkehard Hansen

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Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg

机译：携带乙型肝炎病毒抗原HBsAg的转基因生菜幼苗

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The obtainment of transgenic edible plants carrying recombinant antigens is a desired issue in search for economic alternatives viewing vaccine production. Here we report a strategy for genetic transformation of lettuce plants (Lactuca sativa L.) using the surface antigen HBsAg of hepatitis B virus. Transgenic lettuce seedlings were obtained through the application of a regulated balance of plant growth regulators. Genetic transformation process was acquired by cocultivation of cotyledons with Agrobacterium tumefaciens harboring the recombinant plasmid. It is the first description of a lettuce Brazilian variety "Vitória de Ver?o" genetically modified.

机译：寻找携带疫苗生产的经济替代品是获得携带重组抗原的转基因可食植物的理想问题。在这里，我们报告了使用乙型肝炎病毒的表面抗原HBsAg对生菜植物（Lactuca sativa L.）进行遗传转化的策略。通过应用调节的植物生长调节剂平衡获得了转基因生菜幼苗。通过将子叶与带有重组质粒的根癌农杆菌共培养来获得遗传转化过程。这是对转基因生菜巴西品种“Vitóriade Ver？o”的首次描述。

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《Brazilian Journal of Infectious Diseases》 |2008年第6期|共3页
作者
Ekkehard Hansen;
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中图分类临床医学;
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1. Hepatitis B Virus Surface Antigen (HBsAg)-Positive and HBsAg-Negative Hepatitis B Virus Infection among Mother-Teenager Pairs 13 Years after Neonatal Hepatitis B Virus Vaccination [J] . Qing-Qing Yao, Xiao-Lian Dong, Xue-Cai Wang, Clinical and vaccine immunology: CVI . 2013,第2期

机译：新生乙肝病毒疫苗接种13年后，一对少年对母对乙型肝炎病毒表面抗原（HBsAg）阳性和乙型肝炎病毒阴性的乙型肝炎病毒感染
2. HBsAg/HLA-A2 transgenic mice: a model for T cell tolerance to hepatitis B surface antigen in chronic hepatitis B virus infection. [J] . Loirat D, Mancini Bourgine M, Abastado JP, International immunology. . 2003,第10期

机译：HBsAg / HLA-A2转基因小鼠：慢性乙型肝炎病毒感染中T细胞对乙型肝炎表面抗原的耐受性模型。
3. A human-derived protein SBP (HBsAg-binding protein) can bind to hepatitis B virus surface antigen (HBsAg) and enhance the immune response to hepatitis B virus (HBV) vaccine. [J] . Chongwen Zhang, Li Gong, Yuanyuan Chen, Molecular Immunology . 2013,第1a2期

机译：人衍生的蛋白质SBP（HBsAg结合蛋白）可以与乙型肝炎病毒表面抗原（HBsAg）结合，并增强对乙型肝炎病毒（HBV）疫苗的免疫应答。
4. Fusion Strategy of Influenza A-H5N1 Virus M2e Epitope DNA Sequence to Hepatitis B Virus HBsAg-S Gene [C] . Afifatul Achyar, Tati Kristianti, Sony Suhandono International Conference on Biology, Sciences and Education . 2020

机译：流感A-H5N1病毒M2E表位DNA序列对乙型肝炎病毒HBsAg-S基因的融合策略
5. Functional Characterization of the Lettuce infectious yellows virus (LIYV)-encoded P5, P9 and P26 Proteins and Deep Sequencing Analysis of Crinivirus-immune Transgenic Plants [D] . Qiao, Wenjie. 2018

机译：生菜传染性黄病毒（Liyv）的功能表征 - 尖锐的P5，P9和P26蛋白和Crinivirus免疫转基因植物的深度测序分析
6. Hepatitis B Virus Surface Antigen (HBsAg)-Positive and HBsAg-Negative Hepatitis B Virus Infection among Mother-Teenager Pairs 13 Years after Neonatal Hepatitis B Virus Vaccination [O] . Qing-Qing Yao, Xiao-Lian Dong, Xue-Cai Wang, 2013

机译：新生乙肝病毒疫苗接种13年后一对少年对母对乙型肝炎病毒表面抗原（HBsAg）阳性和乙型肝炎病毒阴性的乙型肝炎病毒感染
7. Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg [O] . Marcondes, Jackson [UNESP], Hansen, Ekkehard 2008

机译：携带乙型肝炎病毒抗原HBsAg的转基因生菜幼苗
8. Guidance for Industry Requalification Method for Reentry of Donors Who Test Hepatitis B Surface Antigen (HBsAg) Positive Following a Recent Vaccination against Hepatitis B Virus Infection. [R] . 2012

机译：在最近接种乙型肝炎病毒感染疫苗后检测乙型肝炎表面抗原（HBsag）阳性的捐赠者再入行业的行业重新认证方法指南。

Transgenic lettuce seedlings carrying hepatitis B virus antigen HBsAg

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