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首页> 外文期刊>Biocontrol Science >Positive Selection in F-Box Domain (lpp0233) Encoded in Legionella pneumophila Strains.
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Positive Selection in F-Box Domain (lpp0233) Encoded in Legionella pneumophila Strains.

机译：在肺炎军团菌菌株中编码的F-Box域（lpp0233）中的阳性选择。

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Recent studies have shown that the genome of Legionella pneumophila is characterized by many foreign genes from a variety of eukaryotes. The eukaryotic like proteins are known to play a role in its multiplication within host cells; however, their evolutionary genetics of L. pneumophila in environments is unknown. In this study, we examined the nonsynonymous/synonymous substitution rate of eukaryotic like domain encoding genes among L. pneumophila strains. In silico analysis revealed that the nonsynonymous/synonymous substitution rate in F-box domain gene (lpp0233) was higher than those in other eukaryotic like domain and protein encoding genes and housekeeping genes. The F-box domain gene sequences in L. pneumophila strains isolated from a natural hot spring were more diversified than those of previously known strains, owing to preferential positive selection.
机译：最近的研究表明，嗜肺军团菌的基因组具有许多来自各种真核生物的外源基因的特征。已知真核样蛋白在宿主细胞内的增殖中发挥作用。然而，它们在环境中的嗜肺乳杆菌的进化遗传学是未知的。在这项研究中，我们检查了嗜肺乳杆菌菌株中真核样结构域编码基因的非同义/同义替代率。在计算机分析中发现，F-box结构域基因（lpp0233）中的非同义/同义替换率高于其他真核样结构域和蛋白质编码基因以及管家基因。由于优先选择阳性，从天然温泉中分离出的嗜肺乳杆菌的F-box结构域基因序列比以前已知的菌株更加多样化。

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