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首页> 外文期刊>Bratislava Medical Journal >Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival – single center results
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Association of the postoperative white blood cells (WBC) count in peripheral blood after radical surgical treatment of left upper lobe non-small cell lung cancer (NSCLC) with overall survival – single center results

机译：左上叶非小细胞肺癌（NSCLC）根治性手术治疗后外周血中术后白细胞（WBC）计数与总体生存率的关联–单中心结果

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INTRODUCTION: The individual patient prognosis after radical surgery for Non-small cell lung cancer (NSCLC) of left upper lobe remains still unclear. The purpose of this study is to evaluate the predictive value of elevated white blood cell count in peripheral blood as early indicator of postoperative NSCLC prognosis. METHODS: A retrospective statistical analysis was performed studying patients subject to radical treatment of left upper lobe NSCLC in period of five years with subsequent one to three-year monitoring of morbidity and mortality of the patient population. The statistical ROC (Receiver Operating Characteristic) analysis of the WBC count in peripheral blood third day after the operation was used to evaluate the relationship with overall survival, with respect to patients surviving for at least 24 months. RESULTS: Based on the results of the ROC analysis with a total area under the curve (AUC) of 0.67, it is possible to confirm that the WBC count established third day after the operation allows us to classify patients into groups according to the 24-month overall survival.CONCLUSION: Our findings confirm the potential of using WBC count to improve current protocols to establish postoperative prognosis for NSCLC of the upper left lobe (Tab. 2, Fig. 1, Ref. 11). Keywords: postoperative white blood cells, peripheral blood, radical surgical treatment, left upper lobe, non-small cell lung cancer, survival-single center results Published online: 15-May-2017 Year: 2017, Volume: 118, Issue: 5 Page From: 299, Page To: 301 doi:10.4149/BLL_2017_073 download file ? AEPress s.r.o Copyright notice: For any permission to reproduce, archive or otherwise use the documents in the ELiS, please contact AEP.
机译：简介：根治性手术后左上叶非小细胞肺癌（NSCLC）的个体患者预后仍不清楚。这项研究的目的是评估外周血白细胞计数升高的预测价值，作为术后NSCLC预后的早期指标。方法：回顾性统计分析研究了接受左上叶非小细胞肺癌根治性治疗的患者，为期五年，随后一到三年监测患者的发病率和死亡率。手术后第三天，对外周血中白细胞计数的统计ROC（接收者操作特征）分析用于评估与存活至少24个月的患者的总体生存率的关系。结果：基于ROC分析的结果，曲线下的总面积（AUC）为0.67，可以确认手术后第三天建立的WBC计数使我们能够根据24-24将患者分为几组。结论：我们的研究结果证实了使用WBC计数来改善当前方案以建立左上叶NSCLC术后预后的潜力（表2，图1，参考文献11）。关键词：术后白细胞，外周血，根治性手术治疗，左上叶，非小细胞肺癌，生存单中心结果在线发布：2017年5月15日年份：2017年，第卷：118页，第5页从：299，页面到：301 doi：10.4149 / BLL_2017_073下载文件？ AEPress s.r.o版权声明：有关复制，存档或以其他方式使用ELiS中的文档的任何许可，请联系AEP。

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