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首页> 外文期刊>British Biotechnology Journal >Antibacterial Activities of Six Medicinal PlantsUsed Traditionally by Saudi People to TreatCommon Diseases
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Antibacterial Activities of Six Medicinal PlantsUsed Traditionally by Saudi People to TreatCommon Diseases

机译：沙特人民传统上用于治疗常见疾病的六种药用植物的抗菌活性

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摘要

Antibiotic resistance is increasing and dangerous problem resulting in a decrease in the used number and fully active antimicrobial agents available to treat infections with multi-drug resistant (MDR) bacteria. Herbal medicines may be an alternative treatment options. This study aimed to evaluate the antibacterial activities of some medicinal plants used traditionally in Saudi Arabia against some pathogenic and MDR bacteria. The antimicrobial activities of water and organic crude extracts were prepared. Out of the 6 plants tested, 5 showed antimicrobial activities against one or more of the tested genera using paper disc diffusion assay. The most active antimicrobial plants were the extract of Azadirachta indica (neem), Zingiber officinale (ginger) Eucalptus globules, Rosmarinus officinalis and Lawsonia inermis with minimal inhibitory concentration (MICs) values ranged from 50-150μg/ml. Lepidium sativium have very weak activity with MIC of ≥200 μg/ml. At 600μg/ml, no toxicity was recorded for all tested extracts except of A. indica extract that showed toxicity (% of mortality ≥50). No antitumor activities for the different plant extracts were recorded against Human gastric cancer SGC-7901 cells. The biological activities may be due to some photochemical compounds including Anthocyanin, Butacyanin, Phytobutanins, Flavonoides, Stetoides and/or Saponins.
机译：抗生素耐药性正在增加并且是危险的问题，导致使用的数量减少以及可用于治疗多重耐药性（MDR）细菌感染的全活性抗菌剂减少。草药可能是替代治疗选择。这项研究旨在评估沙特阿拉伯传统上使用的一些药用植物对某些病原菌和MDR细菌的抗菌活性。制备了水和有机粗提物的抗菌活性。使用纸盘扩散测定法，在测试的6株植物中，有5株对一种或多种测试属显示出抗菌活性。活性最高的抗菌植物是印A（印za），生姜（姜）Eucalptus球，迷迭香（Rosmarinus officinalis）和无核紫草（Lawsonia inermis）的提取物，其最小抑菌浓度（MICs）值范围为50-150μg/ ml。淫羊pi的活性非常弱，MIC≥200μg/ ml。在600μg/ ml的浓度下，所有测试的提取物均未记录到毒性，除了显示毒性（死亡率的≥50％）的A草提取物。没有记录针对人胃癌SGC-7901细胞的不同植物提取物的抗肿瘤活性。生物学活性可能是由于某些光化学化合物所致，包括花青素，Butacyanin，植物丁酮，类黄酮，硬脂酸酯和/或皂苷。

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