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首页> 外文期刊>British Biotechnology Journal >Kerosene: A Study of Serum Vitamin Levels ofFemale Wistar Rats Chronically Exposed
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Kerosene: A Study of Serum Vitamin Levels ofFemale Wistar Rats Chronically Exposed

机译：煤油：长期暴露的雌性Wistar大鼠血清维生素水平的研究

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Background: Kerosene is a commonly available product used for cooking and lighting purposes in many parts of Asia and Africa where it is sold in beverage bottles and jerry cans in both commercial and residential places because of inadequate filling stations. Therefore excessive exposure through both dermal and oral routes is common.Objective: This study is embarked upon to determine the impact of trace amount of kerosene on serum vitamin levels in female Wistar rats. Methods: Kerosene (0.4 ml/kg body weight) was administered to rats either through the oral or dermal route daily for a period of 30 days and the levels of vitamins were estimated using the high performance liquid chromatography technique. Results: Using Student t test only pantothenic acid was not significantly (p0.05) different when oral or dermal group was compared with control, all other vitamins were significantly decreased (p0.05), Moreover, using ANOVA, riboflavin, folic, niacin and vitamins A and D were more depleted in rats in oral route of administration than those in dermal group.Conclusion: The results of this study suggest that exposure to this product either through the oral or dermal route may be detrimental to health as it induced vitamin depletion.
机译：背景：煤油是一种常见的产品，在亚洲和非洲的许多地区用于烹饪和照明目的，由于加油站不足，在商业和住宅场所都以饮料瓶和油罐的形式出售。因此，通过皮肤和口服途径过量接触是普遍的。目的：着手进行这项研究以确定痕量煤油对雌性Wistar大鼠血清维生素水平的影响。方法：每天通过口服或皮肤途径向大鼠施用煤油（0.4 ml / kg体重），持续30天，并使用高效液相色谱技术估算维生素水平。结果：使用Student t检验，口服或真皮组与对照组相比，泛酸无显着差异（p> 0.05），所有其他维生素均显着降低（p <0.05）。此外，使用方差分析，核黄素，叶酸，烟酸结论：本研究结果表明，经口服或经皮肤途径接触该产品的人可能会危害健康，因为它诱导了维生素的生成。消耗。

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