首页> 外文期刊>British Biotechnology Journal >Dietary Consumption of Citrullus lanatus canAmeliorate Infertility Potential of Carica papayaSeeds Extract in Male Rats
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Dietary Consumption of Citrullus lanatus canAmeliorate Infertility Potential of Carica papayaSeeds Extract in Male Rats

机译:日粮柑橘的摄入可改善番木瓜番木瓜种子提取物对雄性大鼠的不育潜力

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Aim: This study examined dietary consumption of Citrullus lanatus as an ameliorative agent against infertility potential of seeds extract of Carica papaya in male wistar rats.Study Design: Eighteen adult male Wistar rats were randomly assigned into three groups of six (n=6): A, B, and C. Group A served as the control group while the other groups served as the treated groups.Place and Duration of Study: This study was carried out in the Animal Holdings of the Department of Anatomy, University of Ilorin, Ilorin, between July, 2014 and October, 2014.Methodology: The Group A animals were given feed and water liberally throughout the study. Group B received 150 mgkg/bwt/d of Carica papaya extract intraperitoneally for 8 weeks, Group C received 150 mgkg/bwt/d of Carica papaya extract intraperitoneally plus Citrullus lanatus orally for 8 weeks. The rats were sacrificed at the end of administration, Testosterone, FSH and LH levels were assayed. Also, semen analysis was carried out to ascertain the level of other parameters.Results: Generally there was significant reduction in the level of Testosterone, FSH and LH in Group B when compared with the Control and Group C. Also, there was significant reduction in the level of sperm count, motility, concentration and morphology in Group B when compared with the Control and Group C. However, there was no significant difference when almost all these parameters were directly compared between Control and Group C.Conclusion: This study has demonstrated that dietary consumption of Citrullus lanatus can ameliorate infertility potential of Carica papaya seeds extract in adult male Wistar rats.
机译:目的:本研究研究了食用日粮柑橘作为改善雄性Wistar大鼠番木瓜种子提取物不育潜能的改良剂。研究设计:将18只成年雄性Wistar大鼠随机分为三组,每组六只(n = 6): A,B和C。A组为对照组,其他组为治疗组。研究的地点和持续时间:这项研究是在Ilorin大学Ilorin大学解剖学系的Animal Holdings中进行的。 (2014年7月至2014年10月)。方法:在整个研究过程中,均给A组动物自由喂食和喂水。 B组腹腔注射番木瓜提取物150 mgkg / bwt / d,共8周; C组腹腔注射腹泻番木瓜提取物150 mgkg / bwt / d,共8周。在给药结束时处死大鼠,测定睾丸激素,FSH和LH水平。此外,还进行了精液分析以确定其他参数的水平。结果:与对照组和C组相比,B组的睾丸激素,FSH和LH水平通常显着降低。与对照组和C组相比,B组的精子数量,活力,浓度和形态水平。但是,直接比较对照组和C组的几乎所有这些参数时,差异无显着性。结论:本研究表明饮食上的饮食习惯可以改善成年雄性Wistar大鼠番木瓜种子提取物的不育潜力。

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