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首页> 外文期刊>BMC Nephrology >Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis
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Reversible renal impairment induced by treatment with the angiotensin II receptor antagonist candesartan in a patient with bilateral renal artery stenosis

机译：血管紧张素Ⅱ受体拮抗剂坎地沙坦治疗双侧肾动脉狭窄患者可逆性肾功能不全

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Background It is well established that ACE-inhibitors should be avoided in patients with renal artery stenosis. In recent years it has also been recommended that caution should be demonstrated when angiotensin II blockers are used in the same type of patients but the evidence is based only on few cases. Results We describe a case where use of the angiotensin II antagonist candesartan (Atacand) induced renal failure in a patient with bilateral renal artery stenosis. The course of the case is enlighted by results from sequential renography, selective renal vein catheterisation for measurement of renin, and angiographic findings. Conclusions In patients with renal artery stenosis the angiotensin II antagonist candesartan should be avoided.
机译：背景众所周知，肾动脉狭窄患者应避免使用ACE抑制剂。近年来，还建议在相同类型的患者中使用血管紧张素II受体阻滞剂时应谨慎行事，但证据仅基于少数病例。结果我们描述了在双侧肾动脉狭窄患者中使用血管紧张素II拮抗剂坎地沙坦（Atacand）引起肾衰竭的情况。顺序性肾脏造影，选择性肾静脉导管测量肾素和血管造影结果的结果为该病例的发展提供了启发。结论肾动脉狭窄患者应避免使用血管紧张素II拮抗剂坎地沙坦。

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