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Acupuncture regulates the glucose metabolism in cerebral functional regions in chronic stage ischemic stroke patients—a PET-CT cerebral functional imaging study

机译:针刺调节慢性缺血性中风患者脑功能区域的葡萄糖代谢——PET-CT脑功能成像研究

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Background Acupuncture has been applied to aid in the recovery of post-stroke patients, but its mechanism is unclear. This study aims to analyze the relationship between acupuncture and glucose metabolism in cerebral functional regions in post-stroke patients using 18 FDG PET-CT techniques. Forty-three ischemic stroke patients were randomly divided into 5 groups: the Waiguan (TE5) needling group, the TE5 sham needling group, the sham point needling group, the sham point sham needling group and the non-needling group. Cerebral functional images of all patients were then acquired using PET-CT scans and processed by SPM2 software. Results Compared with the non-needling group, sham needling at TE5 and needling/sham needling at the sham point did not activate cerebral areas. However, needling at TE5 resulted in the activation of Brodmann Area (BA) 30. Needling/sham needling at TE5 and needling at the sham point did not deactivate any cerebral areas, whereas sham needling at the sham point led to deactivation in BA6. Compared with sham needling at TE5, needling at TE5 activated BA13, 19 and 47 and did not deactivate any areas. Compared with needling at the sham point, needling at TE5 had no associated activation but a deactivating effect on BA9. Conclusion Needling at TE5 had a regulating effect on cerebral functional areas shown by PET-CT, and this may relate to its impact on the recovery of post-stroke patients.
机译:背景针灸已被用于辅助中风后患者的康复,但其机制尚不清楚。本研究旨在通过 18 FDG PET-CT技术分析中风后针刺与脑功能区葡萄糖代谢之间的关系。 43例缺血性中风患者被随机分为5组:外关(TE5)针刺组,TE5假针刺组,假针刺组,假针针刺组和非针刺组。然后使用PET-CT扫描获取所有患者的脑功能图像,并通过SPM2软件进行处理。结果与非针刺组相比,TE5假针刺和假针刺/假针刺均未激活脑区。但是,在TE5处针刺会激活Brodmann Area(BA)30。在TE5处的针刺/假针刺和在假点的针刺都不会使任何大脑区域失活,而在假点处的假针刺会导致BA6失活。与TE5上的假针刺相比,TE5上的针刺激活了BA13、19和47,并且没有使任何区域失活。与假点针刺相比,TE5针刺没有相关的活化作用,但对BA9却有失活作用。结论TE5针刺对PET-CT显示的脑功能区具有调节作用,这可能与其对中风后患者康复的影响有关。

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