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首页> 外文期刊>BMC Pediatrics >Percentile curves for cardiometabolic disease markers in Canadian children and youth: a cross-sectional study
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Percentile curves for cardiometabolic disease markers in Canadian children and youth: a cross-sectional study

机译：加拿大儿童和青少年心脏代谢疾病指标的百分曲线：一项横断面研究

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The objective of this study to develop percentile curves for cardiometabolic disease markers in a population-based sample of Canadian children and youth. The analysis used data from 6116 children and adolescents between 6 and 19?years of age who participated in the Canadian Health Measures Survey cycles 1 (2007/2009), 2 (2009/2011), and 3 (2012/2013). Total cholesterol, HDL cholesterol, and hemoglobin A1c levels as well as fasting levels of triglycerides, insulin, and homeostasis model assessment insulin resistance were measured using standardized procedures. Age- and sex-specific centiles for all markers were calculated using Cole and Green’s LMS method. With the exception of hemoglobin A1c, all markers showed age- and sex-related differences during childhood and adolescence. We have developed centile curves for cardiometabolic disease markers in Canadian children and adolescents and demonstrated age and sex differences that should be considered when evaluating these markers in this age group.
机译：这项研究的目的是在以人口为基础的加拿大儿童和青少年样本中建立心脏代谢疾病标志物的百分曲线。该分析使用了来自6116至19岁的6116岁儿童和青少年的数据，他们参加了加拿大卫生措施调查第1周期（2007/2009），2（2009/2011）和3（2012/2013）。使用标准化程序测量总胆固醇，HDL胆固醇和血红蛋白A1c水平，以及甘油三酸酯，胰岛素和体内稳态模型评估的禁食水平。使用Cole和Green的LMS方法计算了所有标记的年龄和性别差异。除血红蛋白A1c外，所有标记物在儿童期和青春期均显示出与年龄和性别相关的差异。我们已经开发了加拿大儿童和青少年心脏代谢疾病指标的百分曲线，并证明了在该年龄组评估这些指标时应考虑的年龄和性别差异。

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