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首页> 外文期刊>BMC Pediatrics >Attention-deficit/hyperactivity symptoms in preschool children from an E-waste recycling town: assessment by the parent report derived from DSM-IV
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Attention-deficit/hyperactivity symptoms in preschool children from an E-waste recycling town: assessment by the parent report derived from DSM-IV

机译：来自电子垃圾回收镇的学龄前儿童的注意缺陷/多动症状：来自DSM-IV的父母报告评估

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Background To investigate the attention-deficit/hyperactivity disorder (ADHD) status among preschool-aged children in Guiyu, an electronic waste (e-waste) recycling town in Guangdong, China. Methods Two hundred and forty-three parents were surveyed regarding ADHD behaviors in their children (aged 3–7 years) based solely on the DSM-IV criteria. The peripheral blood samples were taken from these children to measure blood lead levels (BLLs) and blood cadmium levels (BCLs). Results 12.8% of children met the criteria for ADHD, of which the inattentive, hyperactive/impulsive and combined subtypes were 4.5%, 5.3% and 2.9% respectively. Of all children, 28.0% had BLLs?≥?10 ug/dL and only 1.2% had BCLs?≥?2 ug/L, levels conventionally considered high. Either modeled by univariate or multivariable analysis, the three ADHD scores (inattentive, hyperactive/impulsive and total scores) calculated from the Parent Rating Scale showed strong positive correlations with BLLs but not with BCLs. Furthermore, children with high BLLs had 2.4 times higher risk of ADHD than those with low BLLs (OR: 2.4 [95% CI: 1.1–5.2]). When each of the 18 categories on the Parent Rating Scale was separately analyzed, children with high BLLs had significant higher risks for positive ADHD symptoms than those with low BLLs in 12 of the 18 categories (ORs ranged from 2.1 [95% CI: 1.1–3.9] to 3.6 [95% CI: 1.7–7.5]). Conclusions This study suggests that environmental lead contamination due to e-waste recycling has an impact on neurobehavioral development of preschool children in Guiyu.
机译：背景技术为了调查中国广东省电子垃圾（电子垃圾）回收镇贵屿市学龄前儿童的注意缺陷/多动障碍（ADHD）状况。方法仅根据DSM-IV标准，对243名父母进行了关于其孩子（3至7岁）ADHD行为的调查。从这些儿童那里采集外周血样本以测量血铅水平（BLL）和血镉水平（BCL）。结果12.8％的儿童符合ADHD标准，其中注意力不集中，过动/冲动和亚型分别为4.5％，5.3％和2.9％。在所有儿童中，有28.0％的BLL≥10 ug / dL，只有1.2％的BCL≥2 ug / L，通常认为是高水平。通过单变量或多变量分析建模，从父母评分量表计算出的三个ADHD得分（注意力不集中，过度活跃/冲动和总得分）与BLL呈强正相关，而与BCL则不呈正相关。此外，高BLL儿童比低BLL儿童的ADHD风险高2.4倍（OR：2.4 [95％CI：1.1-5.2]）。当分别分析“父母评定量表”的18个类别中的每一个类别时，在18个类别中的12个类别中，高BLL的儿童ADHD阳性症状的风险明显高于低BLL的儿童（OR范围为2.1 [95％CI：1.1– 3.9]至3.6 [95％CI：1.7–7.5]）。结论该研究表明，电子垃圾回收所致的环境铅污染对贵屿学龄前儿童的神经行为发育有影响。

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