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Lower limb strength training in children with cerebral palsy – a randomized controlled trial protocol for functional strength training based on progressive resistance exercise principles

机译:脑瘫儿童的下肢力量训练–基于进行性抵抗运动原理的功能性力量训练的随机对照试验方案

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Background Until recently, strength training in children with cerebral palsy (CP) was considered to be inappropriate, because it could lead to increased spasticity or abnormal movement patterns. However, the results of recent studies suggest that progressive strength training can lead to increased strength and improved function, but low methodological quality and incomplete reporting on the training protocols hampers adequate interpretation of the results. This paper describes the design and training protocol of a randomized controlled trial to assess the effects of a school-based progressive functional strength training program for children with CP. Methods/Results Fifty-one children with Gross Motor Function Classification Systems levels I to III, aged of 6 to 13 years, were recruited. Using stratified randomization, each child was assigned to an intervention group (strength training) or a control group (usual care). The strength training was given in groups of 4–5 children, 3 times a week, for a period of 12 weeks. Each training session focussed on four exercises out of a 5-exercise circuit. The training load was gradually increased based on the child's maximum level of strength, as determined by the 8 Repetition Maximum (8 RM). To evaluate the effectiveness of the training, all children were evaluated before, during, directly after, and 6 weeks after the intervention period. Primary outcomes in this study were gross motor function (measured with the Gross Motor Function Measure and functional muscle strength tests) and walking ability (measured with the 10-meter, the 1-minute and the timed stair test). Secondary outcomes were lower limb muscle strength (measured with a 6 RM test, isometric strength tests, and a sprint capacity test), mobility (measured with a mobility questionnaire), and sport activities (measured with the Children's Assessment of Participation and Enjoyment). Spasticity and range of motion were assessed to evaluate any adverse events. Conclusion Randomized clinical trials are considered to present the highest level of evidence. Nevertheless, it is of utmost importance to report on the design, the applied evaluation methods, and all elements of the intervention, to ensure adequate interpretation of the results and to facilitate implementation of the intervention in clinical practice if the results are positive. Trial Registration Trial Register NTR1403
机译:背景技术直到最近,对脑瘫(CP)儿童进行力量训练仍被认为是不合适的,因为这可能导致痉挛加剧或运动方式异常。但是,最近的研究结果表明,渐进式力量训练可导致力量增加和功能改善,但是方法学质量低下以及训练协议报告不完整会妨碍对结果的充分解释。本文介绍了一项随机对照试验的设计和培训方案,以评估针对CP儿童的以学校为基础的渐进式功能强度训练计划的效果。方法/结果招募了年龄在6至13岁之间,具有I至III级总体运动功能分类系统的51名儿童。通过分层随机化,将每个孩子分配到干预组(强度训练)或对照组(常规护理)。对4-5名儿童进行强度训练,每周3次,为期12周。每个培训课程集中于5个练习回路中的四个练习。根据孩子的最大力量水平,逐渐增加训练负荷,这是由8次最大重复训练(8 RM)确定的。为了评估培训的有效性,在干预期之前,之中,之后和之后6周对所有儿童进行了评估。这项研究的主要结果是总体运动功能(通过总运动功能测量和功能性肌肉力量测试测量)和步行能力(通过10米,1分钟和定时楼梯测试测量)。次要结果是下肢肌肉力量(通过6 RM测试,等距力量测试和冲刺能力测试测量),活动能力(通过活动能力问卷测量)和体育活动(通过儿童参与和娱乐评估)进行。评估痉挛和运动范围以评估任何不良事件。结论认为随机临床试验可提供最高水平的证据。尽管如此,最重要的是要报告设计,应用的评估方法和干预措施的所有要素,以确保对结果进行充分的解释,并在结果为阳性时促进在临床实践中实施干预措施。试用注册试用注册NTR1403

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