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Perinatal complications and socio-economic differences in cerebral palsy in Sweden – a national cohort study

机译:瑞典脑瘫的围产期并发症和社会经济差异–一项国家队列研究

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Background There is a controversy regarding the existence of a socio-economic gradient for cerebral palsy. Perinatal emergencies and preterm birth increase the risk for the offspring to develop cerebral palsy. The aim of this study was to investigate the association of socio-economic indicators with cerebral palsy (CP) and the role of perinatal health as mediator of this association. Methods Register study of a national cohort of 805,543 children born 1987–93, including 1,437 children with cerebral palsy that were identified in hospital discharge data from national registers. Socio-economic indicators of the household were taken from the Census of 1985. Logistic regression and chi-square analyses of linearity were used to test hypotheses. Results There was a linear association between the incidence of CP (excluding cases caused by registered injuries or malformations) as well as of major perinatal indicators and the socio-economic status (SES) of the household of the mother (p Conclusion This study suggests that there is a continuous socio-economic gradient for CP in Sweden. Further studies in more complete populations of children with cerebral palsy are needed to confirm this. Perinatal complications seem to mediate some of this gradient.
机译:背景技术关于脑瘫的社会经济梯度的存在存在争议。围产期紧急情况和早产会增加后代发展为脑瘫的风险。这项研究的目的是调查社会经济指标与脑瘫(CP)的关联以及围产期健康作为该关联的中介者的作用。方法登记研究了1987-93年间出生的805543名儿童的全国队列,其中包括从国家登记的出院数据中识别出的1437名脑瘫儿童。该家庭的社会经济指标来自1985年的人口普查。使用Logistic回归和线性线性卡方分析来检验假设。结果CP的发生率(不包括因登记的伤害或畸形引起的病例)以及主要围产期指标与母亲家庭的社会经济状况(SES)之间存在线性关系(p结论本研究表明,瑞典的CP持续存在着社会经济梯度,需要在更完整的脑瘫儿童人群中进行进一步研究以证实这一点,围产期并发症似乎在其中起到一定作用。

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