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首页> 外文期刊>BMC Pediatrics >Resting heart rate as a predictor of metabolic dysfunctions in obese children and adolescents
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Resting heart rate as a predictor of metabolic dysfunctions in obese children and adolescents

机译：静息心率可预测肥胖儿童和青少年的代谢功能障碍

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Background Recent studies have identified that a higher resting heart rate (RHR) is associated with elevated blood pressure, independent of body fatness, age and ethnicity. However, it is still unclear whether RHR can also be applied as a screening for other risk factors, such as hyperglycemia and dyslipidemia. Thus, the purpose of the presented study was to analyze the association between RHR, lipid profile and fasting glucose in obese children and adolescents. Methods The sample was composed of 180 obese children and adolescents, aged between 7-16 years. Whole-body and segmental body composition were estimated by Dual-energy X-ray absorptiometry. Resting heart rate (RHR) was measured by heart rate monitors. The fasting blood samples were analyzed for serum triglycerides, total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and glucose, using the colorimetric method. Results Fasting glucose, TC, triglycerides, HDL-C, LDL-C and RHR were similar in both genders. The group of obese subjects with a higher RHR presented, at a lower age, higher triglycerides and TC. There was a significant relationship between RHR, triglycerides and TC. In the multivariate model, triglycerides and TC maintained a significant relationship with RHR independent of age, gender, general and trunk adiposity. The ROC curve indicated that RHR has a high potential for screening elevated total cholesterol and triglycerides as well as dyslipidemia. Conclusion Elevated RHR has the potential to identify subjects at an increased risk of atherosclerosis development.
机译：背景技术最近的研究已经发现，较高的静息心率（RHR）与血压升高相关，而与体脂，年龄和种族无关。然而，仍不清楚RHR是否也可以用作其他风险因素的筛查，例如高血糖和血脂异常。因此，本研究的目的是分析肥胖儿童和青少年中RHR，脂质分布和空腹血糖之间的关系。方法样本由180名7至16岁的肥胖儿童和青少年组成。通过双能X线吸收法估算全身和节段的身体成分。通过心率监测仪测量静息心率（RHR）。使用比色法对空腹血样的血清甘油三酸酯，总胆固醇（TC），高密度脂蛋白胆固醇（HDL-C），低密度脂蛋白胆固醇（LDL-C）和葡萄糖进行了分析。结果空腹血糖，TC，甘油三酸酯，HDL-C，LDL-C和RHR的性别相似。 RHR较高的肥胖受试者年龄较小，甘油三酯和TC较高。 RHR，甘油三酸酯和TC之间存在显着关系。在多元模型中，甘油三酸酯和TC与RHR保持着显着的关系，而与年龄，性别，一般和躯干肥胖无关。 ROC曲线表明RHR具有筛查总胆固醇和甘油三酸酯升高以及血脂异常的高潜力。结论升高的RHR有潜力识别动脉粥样硬化发展风险增加的受试者。

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