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Resting heart rate: its correlations and potential for screening metabolic dysfunctions in adolescents

机译:静息心率:其相关性和筛查青少年代谢功能障碍的潜力

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Background In pediatric populations, the use of resting heart rate as a health index remains unclear, mainly in epidemiological settings. The aims of this study were to analyze the impact of resting heart rate on screening dyslipidemia and high blood glucose and also to identify its significance in pediatric populations. Methods The sample was composed of 971 randomly selected adolescents aged 11 to 17?years (410 boys and 561 girls). Resting heart rate was measured with oscillometric devices using two types of cuffs according to the arm circumference. Biochemical parameters triglycerides, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and glucose were measured. Body fatness, sleep, smoking, alcohol consumption and cardiorespiratory fitness were analyzed. Results Resting heart rate was positively related to higher sleep quality (β?=?0.005, p?=?0.039) and negatively related to cardiorespiratory fitness (β?=??0.207, p?=?0.001). The receiver operating characteristic curve indicated significant potential for resting heart rate in the screening of adolescents at increased values of fasting glucose (area under curve?=?0.611?±?0.039 [0.534 – 0.688]) and triglycerides (area under curve?=?0.618?±?0.044 [0.531 – 0.705]). Conclusion High resting heart rate constitutes a significant and independent risk related to dyslipidemia and high blood glucose in pediatric populations. Sleep and cardiorespiratory fitness are two important determinants of the resting heart rate.
机译:背景技术在小儿人群中,主要在流行病学背景下,尚不清楚使用静息心率作为健康指数。这项研究的目的是分析静息心率对血脂异常和高血糖筛查的影响,并确定其在儿科人群中的意义。方法样本由971名11至17岁的青少年(男410名,女561名)组成。使用示波计,根据手臂围度,使用两种袖带测量静息心率。测量了甘油三酸酯,总胆固醇,高密度脂蛋白胆固醇,低密度脂蛋白胆固醇和葡萄糖的生化参数。分析了身体脂肪,睡眠,吸烟,饮酒和心肺健康状况。结果静息心率与较高的睡眠质量呈正相关(β= 0.005,p = 0.039),与心肺健康度呈负相关(β= 0.207,p = 0.001)。接收者的工作特征曲线表明,在空腹血糖(曲线下面积?=?0.611?±?0.039 [0.534 – 0.688])和甘油三酸酯(曲线下面积?=?)增加时,筛查青少年时静息心律的潜力很大。 0.618±±0.044 [0.531 – 0.705])。结论高静息心率构成与儿童血脂异常和高血糖相关的重大独立风险。睡眠和心肺健康是静息心率的两个重要决定因素。

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