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首页> 外文期刊>BMC Pregnancy and Childbirth >Providing lipid-based nutrient supplement during pregnancy does not reduce the risk of maternal P falciparum parasitaemia and reproductive tract infections: a randomised controlled trial
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Providing lipid-based nutrient supplement during pregnancy does not reduce the risk of maternal P falciparum parasitaemia and reproductive tract infections: a randomised controlled trial

机译：怀孕期间提供基于脂质的营养补充剂不会降低孕产妇恶性疟原虫寄生虫血症和生殖道感染的风险：一项随机对照试验

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Background Maternal infections are associated with maternal and foetal adverse outcomes. Nutrient supplementation during pregnancy may reduce the occurrence of infections by improving maternal immunity. We aimed to investigate the impact of small-quantity lipid-based nutrient supplement (SQ-LNS) on the occurrence of Plasmodium falciparum parasitaemia during pregnancy and trichomoniasis, vaginal candidiasis and urinary tract infection (UTI) after delivery. Methods Pregnant Malawian women enrolled in the iLiNS-DYAD trial receiving daily supplementation with SQ-LNS, multiple micronutrients (MMN) or iron & folic acid (IFA) from Results The prevalence of P. falciparum parasitaemia was 10.7% at 32 gw, 9% at 36 gw, and 8.3% by RDT and 20.2% by PCR at delivery. After delivery the prevalence of trichomoniasis was 10.5%, vaginal candidiasis was 0.5%, and UTI was 3.1%. There were no differences between intervention groups in the prevalence of any of the infections. Conclusion In this population, SQ-LNS did not influence the occurrence of maternal P. falciparum parasitaemia, trichomoniasis, vaginal candidiasis or UTI. Trial registration Identifier: NCT01239693 (10 November 2010).
机译：背景孕产妇感染与孕产妇和胎儿不良后果有关。怀孕期间补充营养可以通过提高母体免疫力来减少感染的发生。我们旨在研究小剂量脂质基营养补充剂（SQ-LNS）对分娩后妊娠和滴虫，阴道念珠菌病和尿路感染（UTI）发生恶性疟原虫的影响。方法参加iLiNS-DYAD试验的马拉维孕妇，每天补充SQ-LNS，多种微量营养素（MMN）或铁和叶酸（IFA），其结果在32 gw时恶性疟原虫的发生率为10.7％，占9％交付时为36 gw，RDT为8.3％，PCR为20.2％。分娩后毛滴虫病的患病率为10.5％，念珠菌性阴道病的患病率为0.5％，尿路感染的患病率为3.1％。干预组之间任何感染的发生率没有差异。结论在该人群中，SQ-LNS不会影响孕妇恶性疟原虫寄生虫血症，滴虫，阴道念珠菌病或UTI的发生。试用注册标识：NCT01239693（2010年11月10日）。

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