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Depression and glycaemic control among type 2 diabetes patients: a cross-sectional study in a tertiary healthcare facility in Ghana

机译:2型糖尿病患者的抑郁症和血糖控制:加纳三级医疗机构的横断面研究

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Diabetes and depression are both chronic debilitating conditions, and their coexistence has been associated with adverse outcomes. In this study, we investigated the association between glycaemic control and depression in type 2 diabetes (T2DM) patients attending a tertiary healthcare facility in Ghana. In a cross-sectional study design, Patient Health Questionnare-9 (PHQ-9) was used to assess depression in 400 T2DM, aged 30–65?years. Anthropometric characteristics and blood pressure were measured. Venous blood was collected to measure the levels of glycated haemoglobin (HbA1c). The prevalence of depression was 31.3% among T2DM patients. Female gender, being unmarried, frequent intake of alcohol, previous smoking status and insulin use were associated with increased odds of depression, whereas being educated above basic school level was associated with a decreased odds of depression. In a multivariable logistic regression model, being unmarried and poor glycaemic control were associated with an increase in odds of depression after adjusting for age, gender, and social factors. The association between depression and glycaemic control was attenuated when clinical factors were introduced into the model. In our study population, we found that depression is common among Ghanaians with T2DM, and not associated with poor glycaemic control in a fully multivariable-adjusted model.
机译:糖尿病和抑郁症都是慢性衰弱性疾病,它们的共存与不良后果有关。在这项研究中,我们调查了在加纳的一家三级医疗机构中的2型糖尿病(T2DM)患者的血糖控制与抑郁之间的关系。在一项横断面研究设计中,患者健康问题9(PHQ-9)用于评估30岁至65岁的400位T2DM中的抑郁症。测量人体特征和血压。收集静脉血以测量糖化血红蛋白(HbA1c)的水平。在T2DM患者中,抑郁症的患病率为31.3%。女性,未婚,频繁饮酒,以前的吸烟状况和使用胰岛素与抑郁几率增加有关,而受过基础教育以上的教育与降低抑郁几率有关。在多变量logistic回归模型中,未婚和血糖控制不佳与调整年龄,性别和社会因素后的抑郁几率增加有关。将临床因素引入模型后,抑郁症与血糖控制之间的关联减弱。在我们的研究人群中,我们发现抑郁症在加纳T2DM人群中很常见,并且在完全多变量调整的模型中与不良的血糖控制无关。

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