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The Erlangen test of activities of daily living in persons with mild dementia or mild cognitive impairment (ETAM) – an extended validation

机译:患有轻度痴呆或轻度认知障碍(ETAM)的人的日常生活活动的Erlangen测试-扩展验证

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The ability to perform activities of daily living (ADLs) is a central marker in the diagnosis and progression of the dementia syndrome. ADLs can be identified as basic ADLs (BADLs), which are fairly easy to perform, or instrumental ADLs (IADLs), which involve more complex activities. Presently, the only performance-based assessment of IADL capabilities in persons with cognitive impairment is the Erlangen Test of Activities of Daily Living in Persons with Mild Dementia or Mild Cognitive Impairment (ETAM). The aim of the present study was to revalidate the ETAM in persons with mild cognitive impairment (MCI) or mild dementia and to analyze its application to persons with moderate dementia. We used baseline data from a cluster randomized controlled trial involving a sample of 443 users of 34?day-care centers in Germany. We analyzed groups of persons with MCI, mild dementia, and moderate dementia, categorized on the basis of the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). An item analysis was performed, and new discriminant validities were calculated. We computed a confirmatory factor analysis (CFA) to examine the postulated theoretical model of the ETAM with all six items loading on a single IADL factor. This was the first time that the ETAM’s sensitivity to change was analyzed after a time period of 6?months. The overall sample scored on average 17.3 points (SD?=?7.2) on the ETAM (range: 0–30 points). Persons with MCI scored on average 23.2 points, persons with mild dementia scored 18.4 points, and persons with moderate dementia scored 12.9 points, p??.001 (ANOVA). The item analysis yielded good difficulty indices and discrimination powers. The CFA indicated a good fit between the model and the observed data. After 6?months, both the ETAM score at baseline and the change in MMSE score (t0-t1) were significant predictors of the ETAM score at t1. The ETAM is a valid and reliable instrument for assessing IADL capabilities in persons with MCI or mild dementia. It is sensitive to changes in cognitive abilities. The test parameters confirm its application to persons with moderate dementia. Identifier: ISRCTN16412551 (Registration date: 30 July 2014, registered retrospectively).
机译:进行日常生活活动(ADL)的能力是痴呆症综合征诊断和进展的重要标志。可以将ADL识别为相当容易执行的基本ADL(BADL),也可以将其识别为涉及更复杂活动的工具性ADL(IADL)。当前,对认知障碍者的IADL能力进行的唯一基于绩效的评估是对轻度痴呆或轻度认知障碍者(ETAM)日常生活活动的Erlangen测试。本研究的目的是重新验证轻度认知障碍(MCI)或轻度痴呆症患者的ETAM,并分析其在中度痴呆症患者中的应用。我们使用来自一项随机对照试验的基线数据,该试验涉及德国34个日托中心的443位用户的样本。我们分析了MCI,轻度痴呆和中度痴呆的人群,这些人群是根据最低精神状态考试(MMSE)和蒙特利尔认知评估(MoCA)进行分类的。进行了项目分析,并计算了新的判别有效性。我们计算了一个验证性因素分析(CFA),以检查假设的ETAM理论模型,其中所有六个项目都加载在单个IADL因子上。这是ETAM经过6个月的时间后第一次对变化的敏感性进行分析。总体样本在ETAM上平均得分为17.3分(SD?=?7.2)(范围:0–30分)。 MCI患者平均得分为23.2分,轻度痴呆患者得分为18.4分,中度痴呆患者得分为12.9分,p <0.001(ANOVA)。项目分析产生了良好的难度指标和判别力。 CFA表明模型与观察到的数据非常吻合。 6个月后,基线时的ETAM得分和MMSE得分的变化(t0-t1)都是t1时ETAM得分的重要预测指标。 ETAM是评估MCI或轻度痴呆患者IADL能力的有效且可靠的工具。它对认知能力的变化很敏感。测试参数证实其适用于中度痴呆症患者。标识符:ISRCTN16412551(注册日期:2014年7月30日,追溯注册)。

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