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首页> 外文期刊>BMC Psychiatry >Attempted infanticide and suicide inaugurating catatonia associated with Hashimoto’s encephalopathy: a case report
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Attempted infanticide and suicide inaugurating catatonia associated with Hashimoto’s encephalopathy: a case report

机译：企图杀婴和自杀引发桥本脑病相关的卡塔尼亚病：一例病例报告

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Catatonia is a neuropsychiatric syndrome with motor and behavioural symptoms. Though usually occuring in patients with schizophrenia and mood disorders, this syndrome may also be associated with neurological diseases or general medical conditions. Few cases of catatonia associated with autoimmune disorders have been described. Here, we report the case of a 27-year-old woman diagnosed with Hashimoto’s encephalitis (HE) who attempted suicide and infanticide by defenestration. As she presented risk factors for postpartum psychosis, she was treated principally with antipsychotics. Despite adequate treatment for psychosis, symptoms worsened and she developed catatonia. Complementary investigations showed elevated titres of anti-thyroglobulin and anti-thyroperoxidase antibodies (200 and 10 times, respectively, as compared to normal levels) and electroencephalography were suggestive of encephalopathy. In the presence of an otherwise unexplained neuropsychiatric condition, HE was suspected and oral prednisolone was introduced. Psychiatric symptoms improved dramatically within 72?h and the patient was still free of any symptom 3?years later. Catatonia of organic aetiology should always be considered before a psychiatric aetiology especially in case of clinical worsening in spite of adequate psychotropic treatment. To our knowledge, this is the first description of catatonia associated with HE.
机译：卡塔龙尼亚是一种神经精神综合症，伴有运动和行为症状。尽管这种综合征通常发生在精神分裂症和情绪障碍患者中，但也可能与神经系统疾病或一般医疗状况有关。很少有与自身免疫性疾病有关的卡塔尼亚病病例。在这里，我们报告了一名27岁的女性，她被诊断出桥本脑炎（HE），该妇女试图通过开窗自杀和杀婴。当她出现产后精神病的危险因素时，主要接受抗精神病药治疗。尽管对精神病进行了充分的治疗，但症状却加重了，她发展为卡塔尼亚。补充调查显示，抗甲状腺球蛋白和抗甲状腺氧化酶抗体的滴度升高（分别是正常水平的200和10倍），脑电图提示脑病。在存在无法解释的神经精神疾病的情况下，怀疑有HE，并引入了口服泼尼松龙。精神症状在72小时内显着改善，并且3年后患者仍然没有任何症状。在精神病学之前应始终考虑有机病因学的卡塔托尼亚病，尤其是在尽管进行了适当的精神病治疗而临床恶化的情况下。据我们所知，这是与HE有关的卡塔尼亚的首次描述。

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