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首页> 外文期刊>Brazilian Journal of Otorhinolaryngology >Brainstem auditory evoked potentials in children with lead exposure
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Brainstem auditory evoked potentials in children with lead exposure

机译：铅暴露儿童脑干听觉诱发电位

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Introduction: Earlier studies have demonstrated an auditory effect of lead exposure in children, but information on the effects of low chronic exposures needs to be further elucidated. Objective: To investigate the effect of low chronic exposures of the auditory system in children with a history of low blood lead levels, using an auditory electrophysiological test. Methods: Contemporary cross-sectional cohort. Study participants underwent tympanometry, pure tone and speech audiometry, transient evoked otoacoustic emissions, and brainstem auditory evoked potentials, with blood lead monitoring over a period of 35.5 months. The study included 130 children, with ages ranging from 18 months to 14 years, 5 months (mean age 6 years, 8 months ± 3 years, 2 months). Results: The mean time-integrated cumulative blood lead index was 12 µg/dL (SD ± 5.7, range:2.433). All participants had hearing thresholds equal to or below 20 dBHL and normal amplitudes of transient evoked otoacoustic emissions. No association was found between the absolute latencies of waves I, III, and V, the interpeak latencies I-III, III-V, and I-V, and the cumulative lead values. Conclusion: No evidence of toxic effects from chronic low lead exposures was observed on the auditory function of children living in a lead contaminated area.
机译：简介：较早的研究表明，铅对儿童的听觉影响，但有关慢性低暴露影响的信息有待进一步阐明。目的：通过听觉电生理测试，探讨低长期铅暴露史儿童的听觉系统长期暴露的影响。方法：当代横断面队列研究。研究参与者进行了鼓室描记法，纯音和语音测听，短暂诱发的耳声发射以及脑干听觉诱发电位，并在35.5个月的时间内进行了血铅监测。该研究包括130名儿童，年龄从18个月至14岁，5个月不等（平均年龄6岁，8个月±3岁，2个月）。结果：平均时间累积血铅指数为12 µg / dL（SD±5.7，范围：2.433）。所有参与者的听力阈值均等于或低于20 dBHL，瞬态诱发的耳声发射的正常幅度。在波I，III和V的绝对延迟，峰间延迟I-III，III-V和I-V与累积超前值之间未发现关联。结论：长期低铅暴露对生活在铅污染地区的儿童的听觉功能没有观察到毒性作用的证据。

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