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首页> 外文期刊>Brazilian Journal of Otorhinolaryngology >Temporal bone paragangliomas: 15 years experience ☆
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Temporal bone paragangliomas: 15 years experience ☆

机译：颞骨神经节瘤：15年经验☆

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Introduction Temporal bone paragangliomas (TBPs) are benign tumors arising from neural crest cells located along the jugular bulbus and the tympanic plexus. In general surgical excision, radiotherapy and wait-and-scan protocols are the main management modalities for TBPs. Objective In this paper we aim to present our clinical experience with TBPs and to review literature data. Methods The patients who were operated for tympanomastoid paraganglioma (TMP) or tympanojugular paraganglioma (TJP) in our clinic in the last 15 years were enrolled in the study. A detailed patient's charts review was performed retrospectively. Results There were 18 (52.9%) cases with TMPs and 16 (47.1%) cases with TJPs, a total of 34 patients operated for TBPs in this time period. The mean age was 50.3 ± 11.7 (range 25-71 years). The most common presenting symptoms were tinnitus and hearing loss for both TMPs and TJPs. Gross total tumor resection was achieved in 17 (94.4%) and 10 (62.5%) cases for TMPs and TJPs, respectively. Five patients (31.2%) with TJP experienced facial palsy following the operation. For all the patients the mean follow-up period was 25.8 months (range 4-108 months). Conclusion In conclusion, based on our findings and literature review, total surgical excision alone or with preoperative embolization is the main treatment modality for TBPs. However radiotherapy, observation protocol and subtotal resection must be considered in cases of preoperative functioning cranial nerves, large tumors and advanced age.
机译：简介颞骨旁神经节瘤（TBP）是良性肿瘤，由沿颈球和鼓膜神经丛的神经c细胞引起。在一般的手术切除中，放射治疗和等待扫描方案是TBP的主要管理方式。目的在本文中，我们旨在介绍我们在TBP方面的临床经验并回顾文献数据。方法回顾性分析我院最近15年因鼓膜乳突旁神经节瘤（TMP）或鼓室颈旁神经节瘤（TJP）手术的患者。回顾性地进行了详细的患者病历检查。结果共有18例（52.9％）的TMPs患者和16例（47.1％）的TJPs患者，在此期间共有34例进行了TBPs手术。平均年龄为50.3±11.7（范围为25-71岁）。对于TMP和TJP，最常见的症状是耳鸣和听力下降。 TMP和TJP分别达到17例（94.4％）和10例（62.5％）的肿瘤总切除率。手术后有5例TJP患者（31.2％）出现了面神经麻痹。对于所有患者，平均随访期为25.8个月（范围4-108个月）。结论总之，根据我们的发现和文献综述，单独的全手术切除或术前栓塞是TBP的主要治疗方式。但是，在术前颅神经功能正常，肿瘤较大和高龄的情况下，必须考虑放疗，观察方案和大部切除。

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