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首页> 外文期刊>Cadernos de Saúde Pública >Hospitalizations and deaths from drug poisoning and adverse reactions in Brazil: an analysis from 2000 to 2014Mortalidad e internamientos hospitalarios por intoxicaciones y reacciones adversas a medicamentos en Brasil: análisis de 2000 a 2014
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Hospitalizations and deaths from drug poisoning and adverse reactions in Brazil: an analysis from 2000 to 2014Mortalidad e internamientos hospitalarios por intoxicaciones y reacciones adversas a medicamentos en Brasil: análisis de 2000 a 2014

机译：巴西药物中毒和不良反应导致的住院和死亡：2000年至2014年的分析巴西中毒和药物不良反应导致的死亡率和住院：2000年至2014年的分析

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In recent years, drug poisoning and adverse reactions have been an important cause of hospitalization and mortality and a major public health issue. The aim of this study was to describe trends in hospitalizations and deaths from drug poisoning and adverse reactions from 2000 to 2014. Data were from the Mortality Information System (SIM) and Information System on Authorizations for Hospital Admissions of the Brazilian Unified National Health System (SIH-SUS), and the study population was analyzed by sex, region of residence, and age bracket. Events were defined according to ICD-10 codes. The analysis of trends in the historical series used Prais-Winsten generalized linear regression with correction for first order autocorrelation effect. Both the hospitalizations and deaths during the study period showed upward trends. The analysis by regions maintained the upward trends for both events in the South and Southeast regions. Analysis according to age brackets showed downward trends in children under five years in both events, upward trend in deaths in individuals over four years of age, and an upward trend in hospitalizations in the age bracket from 20 to 59 years. Drug poisoning and adverse reactions contribute significantly to hospitalizations and deaths in Brazil, and the SIM and SIH-SUS are data sources with satisfactory quality for population-based studies on hospital morbidity and mortality in the country.
机译：近年来，药物中毒和不良反应一直是住院和死亡的重要原因，也是主要的公共卫生问题。这项研究的目的是描述2000年至2014年期间因药物中毒和不良反应而住院和死亡的趋势。数据来自巴西统一国家卫生系统的死亡率信息系统（SIM）和住院许可授权信息系统（ SIH-SUS），并按性别，居住地区和年龄段对研究人群进行了分析。事件是根据ICD-10代码定义的。历史序列趋势的分析使用Prais-Winsten广义线性回归，并对一阶自相关效应进行校正。研究期间的住院和死亡人数均呈上升趋势。按地区进行的分析保持了南部和东南部地区两个事件的上升趋势。根据年龄段进行的分析显示，两种情况下5岁以下儿童的下降趋势，4岁以上人群的死亡人数呈上升趋势，而20至59岁年龄段的住院人数呈上升趋势。在巴西，药物中毒和不良反应极大地导致了住院和死亡，SIM和SIH-SUS是该国基于人群的医院发病率和死亡率研究的令人满意的数据来源。

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