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首页> 外文期刊>Cancer and Clinical Oncology >Stereotactic Brain Biopsy or Bronchoscopic/Transthoracic Needle Biopsy for Diagnosis of Metastatic Cancer Presenting Simultaneously in Lung and Brain: A Comparison of Safety and Efficacy
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Stereotactic Brain Biopsy or Bronchoscopic/Transthoracic Needle Biopsy for Diagnosis of Metastatic Cancer Presenting Simultaneously in Lung and Brain: A Comparison of Safety and Efficacy

机译：立体定向脑活检或支气管镜/经胸针活检诊断同时存在于肺和脑的转移性癌症：安全性和有效性的比较

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Background: When patients present with sim ultaneous lung and brain lesions consistent with metastases, it is often presumed that it is safer and less invasive to biopsy the lung lesion. Objective: To determine whether lung biopsy or stereotactic brain biopsy has a higher diagnostic yield and lower morbidity for tissue diagnosis in patients with simultaneous brain and lung lesions. Methods: Retrospective review of the author’s stereotactic biopsy series and of the literature on brain and lung biopsies for suspected malignancy. Results: The overall diagnostic yield for bronchoscopic lung biopsy ranged from 44% to 88% and the pneumothorax rate from 1.2% to 8%. No deaths were reported. The overall diagnostic yield for transthoracic lung biopsy ranged from 74% to 96% and pneumothorax rate from 2.2% to 8%. No deaths were reported. The overall diagnostic yield for stereotactic brain biopsy ranged from 90.6% to 99.3% when all potential diagnoses are included. Complication rates ranged from 0.6% to 4.8% with mortality from 0% to 1.5%. Several series reported no mortality. Conclusion: Stereotactic brain biopsy has a higher diagnostic yield and a lower complication rate, but a higher mortality. The inclusion of diagnoses other than metastases in the reported series may account for some of the reported mortality. When lung and brain lesions are detected simultaneously, stereotactic biopsy is an excellent option for tissue diagnosis.
机译：背景：当患者同时出现肺部和脑部同时转移的病变时，通常认为对肺部病变进行活检更安全，侵入性更小。目的：确定在同时患有脑和肺部病变的患者中，肺活检或立体定向脑活检对组织诊断的诊断率较高，而发病率较低。方法：回顾性回顾作者的立体定向活检系列以及有关可疑恶性肿瘤的脑和肺活检的文献。结果：支气管镜肺活检的总诊断率为44％至88％，气胸率为1.2％至8％。没有死亡的报道。经胸肺活检的总诊断率为74％至96％，气胸率为2.2％至8％。没有死亡的报道。包括所有可能的诊断在内，立体定向脑活检的总诊断率为90.6％至99.3％。并发症发生率从0.6％到4.8％，死亡率从0％到1.5％。多个系列均未报告死亡。结论：立体定向脑活检具有较高的诊断率和较低的并发症发生率，但死亡率较高。在报告的系列中包括转移以外的诊断可能会导致某些报告的死亡率。当同时检测到肺部和脑部病变时，立体定向活检是组织诊断的绝佳选择。

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