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首页> 外文期刊>Canadian Journal of Pure and Applied Sciences >Interaction of Sodium Fluoride on Aluminium Chloride induced Effects on Cholinesterase Activity in Tissues of the Fish Oreochromis mossambicus
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Interaction of Sodium Fluoride on Aluminium Chloride induced Effects on Cholinesterase Activity in Tissues of the Fish Oreochromis mossambicus

机译：氟化钠与氯化铝的相互作用对莫桑比克鱼（Oreochromis mossambicus）组织中胆碱酯酶活性的影响

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摘要

The combined action of sodium fluoride and aluminum chloride on Cholinesterase activity was studied by exposing fresh water fish Oreochromis mossambicus to varying concentration at different time intervals. In cerebellum, Cholinesterase activity decreased at 150ppm and 337.5ppm of aluminum chloride. In 225ppm of aluminum chloride no significant inhibition was found. In the brain tissue of medulla oblongata, Cholinesterase activity was significantly increased at (P<0.05) at 48 hrs and 96 hrs for 150ppm for aluminium chloride. The Cholinesterase activity significantly decreased (P<0.05) for 225ppm and 337.5ppm of aluminium chloride exposure the same was observed for all duration of exposures. Cholinesterase activity was significantly high at all duration of exposure. In the liver tissue the acetyl chloine activity decreased at all low concentration of exposure with respect to aluminium chloride. Whereas higher concentration (337.5ppm) significant (p<0.05) enzyme inhibition was decreased at 96hrs and 21 day of exposure. Sodium fluoride significantly (P<0.001) increased the enzyme activity at 24hrs and 96hrs of exposure alone. But the effect was counteracted when same animal was exposed to aluminium chloride for all duration of exposure periods.
机译：通过在不同的时间间隔将淡水鱼莫桑比克罗非鱼暴露于不同浓度下，研究了氟化钠和氯化铝对胆碱酯酶活性的联合作用。在小脑中，胆碱酯酶活性在氯化铝150ppm和337.5ppm时降低。在225ppm的氯化铝中，没有发现明显的抑制作用。在延髓的脑组织中，氯化铝的浓度为150ppm时，在48h和96h时，胆碱酯酶活性显着增加（P <0.05）。对于225ppm和337.5ppm的氯化铝，胆碱酯酶活性显着降低（P <0.05），在所有暴露时间内均观察到相同。在所有暴露期间，胆碱酯酶活性均显着较高。在肝脏组织中，相对于氯化铝，乙酰氯活性在所有低浓度暴露下均降低。而较高浓度（337.5ppm）的显着（p <0.05）酶抑制作用在暴露96小时和21天时降低。氟化钠在单独暴露的24小时和96小时显着提高（P <0.001）。但是，当同一只动物在所有暴露期间都暴露于氯化铝时，这种作用被抵消。

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