首页> 外文期刊>Canadian Journal of Pure and Applied Sciences >PHYTOCHEMICAL SCREENING AND EVALUATION OF STEM BARK EXTRACT OF KHAYA SENEGALENSIS (MELIACEAE) ON METHICILLIN RESISTANT STAPHYLOCCOCUS AREUS
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PHYTOCHEMICAL SCREENING AND EVALUATION OF STEM BARK EXTRACT OF KHAYA SENEGALENSIS (MELIACEAE) ON METHICILLIN RESISTANT STAPHYLOCCOCUS AREUS

机译:耐甲氧西林金黄色葡萄球菌的Khaya Seneglensis(Meliaceae)干树皮提取物的理化筛选和评价

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Khaya senegalensis is an herbal medicinal plant, used locally in Nigeria and South Africa for the treatment of cough andsexually transmitted diseases. This antibacterial activity prompted the phytochemical and antibacterial investigation ofthis herbal plant. The stem bark of K. senegalensis was subjected to phytochemical studies using standard experimentalprocedures testing for secondary metabolites. The crude extract was evaluated for its antimicrobial activity usingmethicillin resistant strains of Staphyloccocus aureus MRSA. The result of the study revealed the presence of alkaloids,saponins, tannins and flavonoids in the plant extract. The extract exhibited significant antibacterial and MRSA activitiesagainst the tested organisms. The study therefore provides natural source for drugs used for the treatment of methicillinresistant strains (MRSA) infections.
机译:塞内加尔Khaya是一种草药,在尼日利亚和南非本地用于治疗咳嗽和性传播疾病。这种抗菌活性促进了该草药植物的植物化学和抗菌研究。使用标准实验程序对次生代谢产物进行测试,对塞内加尔甘蓝的茎皮进行了植物化学研究。使用耐甲氧西林的金黄色葡萄球菌MRSA菌株评估粗提物的抗菌活性。研究结果表明,植物提取物中存在生物碱,皂苷,单宁和类黄酮。提取物对被测生物具有显着的抗菌和MRSA活性。因此,该研究为用于治疗耐甲氧西林菌株(MRSA)感染的药物提供了天然来源。

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