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首页> 外文期刊>Cancer Medicine >Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015
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Analysis of population‐based colorectal cancer screening in Guangzhou, 2011‐2015

机译:2011-2015年广州市基于人群的大肠癌筛查分析

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Objective To analyze the detection rates of colorectal cancer (CRC) and polyps by population‐based screening in Guangzhou. Methods From January 2011 to December 2015, the residents aged 30‐79 were selected for CRC screening. The residents were conducted Questionnaires and/or FOBT to assess high‐risk groups, the free colonoscopy examination was recommended, and the results were evaluated in detail. Results There were 98?927 residents involving screening, 5306 high‐risk residents identified (males 1859 and females 3447), and 4713 subjects underwent colonoscopy (males 1690 and females 3023). CRC was seen in 55 individuals (males 28 and females 27), and the detection rates in male were higher than in female ( P ?=?0.019). And the detection rates increasing with age, for people over 60?years old, were obviously higher than those younger ( x 2 ?=?18.64, P ?=?0.000924). The polyps were seen in 1458 (30.94%) cases, and 1420 subjects received pathological examination (adenomas 971 and non‐adenomatous polyps 449). Advanced adenomas were seen in 462 cases (males 240 and females 222) and 509 cases of non‐advanced adenomas (males 255 and females 254). For advanced adenomas, the detection rates in male were higher than female (14.20% vs 7.34%, P ?=?2.64?×?10 ?14 ). For the detection rates of adenomas or advanced adenomas by age, the people over 40?years were higher than younger (20.91% vs 3.61% P ?=?7.87?×?10 ?6 ; 9.94% vs 2.41%, P ?=?0.009). Conclusions For Guangzhou residents, the detection rates of CRC and adenoma were 1.17% and 20.60%. The detection rates of CRC increasing with age, for people over 60?years old, were obviously higher than those younger. But for people over 40?years, the detection rate of adenoma and advanced adenoma was higher than younger. So for people over 40?years, the CRC screening is recommended.
机译:目的通过人群筛查广州市大肠癌和息肉的检出率。方法从2011年1月至2015年12月,选择30-79岁的居民进行CRC筛查。对居民进行问卷调查和/或FOBT评估高危人群,建议进行免费结肠镜检查,并对结果进行详细评估。结果共有98?927名居民进行了筛查,确定了5306名高危居民(男性1859,女性3447),以及4713名接受了结肠镜检查的受试者(男性1690,女性3023)。在55个人(男性28和女性27)中发现了CRC,男性的检出率高于女性(P = 0.019)。而且,对于60岁以上的人群,检出率随着年龄的增长而增加,明显高于年轻人(x 2 = 18.64,P = 0.00924)。息肉见1458例(30.94%),有1420例接受了病理检查(腺瘤971例和非腺瘤性息肉449例)。 462例(男性240例,女性222例)和509例非晚期腺瘤(男性255例,女性254例)可见晚期腺瘤。对于晚期腺瘤,男性的检出率高于女性(14.20%vs 7.34%,P == 2.64××10 = 14)。对于按年龄划分的腺瘤或晚期腺瘤检出率,40岁以上的人群高于年轻人(20.91%vs 3.61%P?=?7.87?×?10?6; 9.94%vs 2.41%,P?=? 0.009)。结论广州市居民CRC和腺瘤检出率分别为1.17%和20.60%。对于60岁以上的人群,CRC的检出率随着年龄的增长而增加,显然高于年轻的人群。但是对于40岁以上的人群,腺瘤和晚期腺瘤的检出率要高于年轻。因此,对于40岁以上的人群,建议进行CRC筛查。

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