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Serial Changes in Pulmonary Hemodynamics During Pregnancy: A Non-Invasive Study Using Doppler Echocardiography

机译:妊娠期间肺血流动力学的系列变化:使用多普勒超声心动图的非侵入性研究

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Background: This study aimed to describe the pulmonary hemodynamic changes during the course of pregnancy and to observe any significant effects on symptomatology and outcome of pregnancy due to these changes.Methods: A total of 75 patients were recruited for the study, 60 pregnant women from first trimester to third trimester and 6 weeks of puerperium for the study group and 15 non-pregnant patients. All the subjects were interrogated about their complaints like excessive cough, exertional dyspnea, palpitations, orthopnea, syncope, exertional chest pain and lower extremity edema along with their duration. Baseline investigations, echocardiography (ECG) and Doppler echo were done.Results: The commonest symptoms were palpitations (40%), exertional dyspnea (35%) and lower extremity edema (47%). Palpitations and dyspnea were also present in control group. Right axis deviation was the next most common abnormality in study group (12.3% patients). Pulmonary blood flow was decreased by more than 50% of predelivery value at the end of puerperium. Fall in pulmonary vascular resistance returned to base line values. Increased pulmonary artery pressure was seen during the pregnancy, which was not statistically significant.Conclusion: During pregnancy, though the pulmonary blood flow increases significantly, the pulmonary artery pressure remains unchanged due to substantial fall in pulmonary vascular resistance in early gestation.Cardiol Res. 2016;7(1):25-31doi: http://dx.doi.org/10.14740/cr448w
机译:背景:本研究旨在描述妊娠过程中的肺血流动力学变化,并观察这些变化对妊娠症状和妊娠结局的任何重大影响。方法:共招募75名患者,其中60名孕妇研究组和15名非妊娠患者的妊娠中期至妊娠中期和产褥期6周。所有受试者均受到询问,包括咳嗽过多,劳累性呼吸困难,心pit,正气呼吸,晕厥,劳累性胸痛和下肢水肿以及持续时间。结果:最常见的症状是心pal(40%),劳累性呼吸困难(35%)和下肢水肿(47%)。对照组也出现心pit和呼吸困难。右轴偏离是研究组中次常见的异常(12.3%的患者)。在产褥期结束时,肺血流量下降了超过分娩前值的50%以上。肺血管阻力下降至基线值。妊娠期间发现肺动脉压力升高,但无统计学意义。结论:妊娠期间,尽管肺血流量显着增加,但由于妊娠早期肺血管阻力的大幅下降,肺动脉压力保持不变。 2016; 7(1):25-31doi:http://dx.doi.org/10.14740/cr448w

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