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首页> 外文期刊>Case Reports in Pathology >Langerhans Cell Histiocytosis of the Thyroid with Multiple Cervical Lymph Node Involvement Accompanying Metastatic Thyroid Papillary Carcinoma
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Langerhans Cell Histiocytosis of the Thyroid with Multiple Cervical Lymph Node Involvement Accompanying Metastatic Thyroid Papillary Carcinoma

机译：甲状腺多发性颈淋巴结受累伴转移性甲状腺乳头状癌的朗格汉斯细胞组织细胞增生症

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A 37-year-old male case was admitted with goiter. Ultrasonography of thyroid showed a 5 cm cystic nodule in the left lobe with a 1.5 cm solid component. Fine needle aspiration biopsy revealed atypia of undetermined significance or follicular lesion. The patient was operated on. The pathological diagnosis was reported as papillary thyroid carcinoma. The immunohistochemical examination showed multiple foci of Langerhans cell histiocytosis involving both lobes. The patient died due to cardiac arrest with respiratory causes in the early postoperative period. Langerhans cell histiocytosis is a rare primary condition which involves abnormal clonal proliferation of Langerhans cells in various tissues and organs. Thyroid involvement is infrequently seen. Although the etiology is unknown, genetic components may be linked to the disease. It is also associated with a family history of thyroid disease. Papillary thyroid carcinoma is the most common malignant epithelial tumor of the thyroid gland. Langerhans cell histiocytosis presenting with papillary thyroid carcinoma is rare. The privilege of our case is langerhans cell histiocytosis of the thyroid with multiple cervical lymph node involvement accompanying cervical lymph node metastatic thyroid papillary carcinoma.
机译：一例37岁的男性病例被甲状腺肿收治。甲状腺超声检查显示左叶有一个5 cm的囊性结节，固体成分为1.5 cm。细针穿刺活检显示非典型性意义不明或滤泡性病变。病人接受了手术。病理诊断为甲状腺乳头状癌。免疫组织化学检查显示朗格汉斯细胞组织细胞增生病灶涉及两个叶。该患者在术后早期因心脏骤停死于呼吸原因。朗格汉斯细胞组织细胞增生是一种罕见的原发性疾病，涉及朗格汉斯细胞在各种组织和器官中的异常克隆增殖。很少见到甲状腺受累。尽管病因不明，但遗传成分可能与疾病有关。它也与甲状腺疾病的家族史有关。甲状腺乳头状癌是甲状腺最常见的恶性上皮肿瘤。伴有甲状腺乳头状癌的朗格汉斯细胞组织细胞增生症很少。我们的病例的特权是伴随多个颈淋巴结受累伴随着颈淋巴结转移性甲状腺乳头状癌的甲状腺Langerhans细胞组织细胞增生。

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