The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres

Luisa Kelmer C?rtesde Barros Silveira; Felipe Ladeirade Oliveira; Thais de Barros CastroAlves; Maria Lourdes CandelaRambaldi; Felipe Cupertino deAndrade; Santuzza de CarvalhoKelmer; Fabio CuiabanoBarbosa

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The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres

机译：别嘌醇在治疗聚甲基丙烯酸甲酯微球引起的异物肉芽肿中的治疗作用

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Injectable polymethylmethacrylate (PMMA) microspheres are nonbiodegradable and too large for macrophage phagocytosis. There are several complications possible to happen, like chronic nonspecific inflammatory reactions, lip stiffness, infection, and granulomas. The occurrence of granulomas can lead to a not aesthetic result, making some extreme changes in the patient’s life. The objective of this case report is to describe the successful treatment of foreign body granulomas caused by polymethylmethacrylate microspheres using allopurinol, an innovative therapy for this condition.

机译：可注射的聚甲基丙烯酸甲酯（PMMA）微球不可生物降解，对于巨噬细胞吞噬作用而言太大。可能发生多种并发症，例如慢性非特异性炎症反应，嘴唇僵硬，感染和肉芽肿。肉芽肿的发生可能导致不美观的结果，使患者的生活发生一些极端变化。本病例报告的目的是描述使用别嘌呤醇成功治疗由聚甲基丙烯酸甲酯微球引起的异物肉芽肿，这是一种针对这种情况的创新疗法。

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《Case Reports in Dermatological Medicine》 |2012年第10期|共3页
作者
Luisa Kelmer C?rtesde Barros Silveira; Felipe Ladeirade Oliveira; Thais de Barros CastroAlves; Maria Lourdes CandelaRambaldi; Felipe Cupertino deAndrade; Santuzza de CarvalhoKelmer; Fabio CuiabanoBarbosa;
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6. The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres [O] . Luisa Kelmer Côrtes de Barros Silveira, Felipe Ladeira de Oliveira, Thais de Barros Castro Alves, 2012

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The Therapeutic Benefit of Allopurinol in the Treatment of Foreign Body Granulomas Caused by Polymethylmethacrylate Microspheres

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