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Cytoskeleton and Golgi-apparatus interactions: a two-way road of function and structure

机译:细胞骨架与高尔基体的相互作用:功能和结构的两条道路

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Abstract: The Golgi apparatus is the result of a complex and dynamic interaction between a large variety of molecules that determine its architecture, protein and lipid transports, and those that integrate signals from outside and inside the cell. The cytoskeleton facilitates the functional integration of all these processes. Association and coordination between microtubules and actin filaments, as well as their respective binding and regulatory proteins, are clearly necessary for Golgi structure and function. Protein sorting, membrane fission and fusion, and the motion of Golgi-derived transport carriers are all affected by both cytoskeleton elements.
机译:摘要:高尔基体是多种分子之间复杂而动态的相互作用的结果,这些分子决定了其结构,蛋白质和脂质的运输,以及那些整合了细胞内外信号的分子。细胞骨架促进所有这些过程的功能整合。微管和肌动蛋白丝之间的关联和协调,以及它们各自的结合和调节蛋白,显然是高尔基体结构和功能所必需的。蛋白质分选,膜裂变和融合以及高尔基体运输载体的运动都受两个细胞骨架元件的影响。

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