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首页> 外文期刊>Case Reports in Veterinary Medicine >A Case of Contagious Ecthyma (Orf Virus) in a Nonmanipulated Laboratory Dorset Sheep (Ovis aries)
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A Case of Contagious Ecthyma (Orf Virus) in a Nonmanipulated Laboratory Dorset Sheep (Ovis aries)

机译：一例未经处理的多塞特郡绵羊（绵羊）传染性c疮（Orf病毒）病例

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An approximately 5-month-old laboratory wether, originating from a local vendor with a closed flock and maintained on a preventative medicine plan, presented with a continuum of lesions from hemorrhagic papules, vesicles, and pustules, to multifocal necrotic scabs at the commissure of the lips, medial canthus of the left eye, and distal prepuce. A presumptive diagnosis of Orf virus (ORFV) was made and the sheep was euthanized. A full necropsy was performed, and histopathological evaluation of affected tissues revealed multifocal-to-coalescing necrotizing and proliferative cheilitis and dermatitis with eosinophilic intracytoplasmic inclusion bodies. Electron microscopy findings revealed degenerate keratinocytes containing numerous typical 200–300 nm wide cytoplasmic parapoxvirus virions, confirming the diagnosis of ORFV. We believe that this animal developed a clinical case of ORFV either due to an adverse reaction to an ORFV vaccine, or this animal had a case of preexisting ORFV which manifested after arrival at our facility.
机译：一个大约5个月大的实验室，从一个封闭的羊群的当地供应商那里购得，并保持着预防医学计划，并呈现出从出血性丘疹，囊泡和脓疱到多灶性坏死性结ab的连续病灶。嘴唇，左眼内侧can和包皮远端。进行了Orf病毒（ORFV）的推定诊断，并对绵羊实施了安乐死。进行了完整的尸检，并且对受影响的组织进行了组织病理学评估，结果显示嗜酸性的胞浆内包涵体可发生多灶到丛集性坏死性增生性唇炎和皮炎。电子显微镜检查发现，变性的角质形成细胞含有许多典型的200-300 nm宽的胞质副痘病毒颗粒，证实了ORFV的诊断。我们认为，这只动物由于对ORFV疫苗的不良反应而发展为ORFV的临床病例，或者这只动物在到达我们的工厂后就出现了先前存在的ORFV病例。

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