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Canine Bilateral Conjunctivo-Palpebral Dermoid: Description of Two Clinical Cases and Discussion of the Relevance of the Terminology

机译:犬双眼结膜-睑缘皮样皮肤:两例临床病例的描述及术语相关性的讨论

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Two young dogs were presented for the evaluation of an abnormally haired appearance of both eyes since adoption. In one dog, the lesions were symmetrical and appeared as disorganized skin tissue located on the cutaneous aspect of the lateral portion of both lower eyelids, and continuing to the palpebral and the bulbar conjunctiva, thus forming continuous lesions. In the other dog, a similar lesion was present in the right eye (OD), but the lesion of the left eye (OS) was of discontinuous, disorganized skin tissue located midway on the lower eyelid and on the lateral bulbar conjunctiva. The lesions were surgically removed and routinely processed for histopathological analysis. Definitive diagnosis was conjunctivo-palpebral dermoids for each dog. Dermoids are usually considered to be choristoma (normal tissue in an abnormal location) when they are located on the ocular surface (cornea and/or conjunctiva) and as hamartoma when located on the palpebral skin. The lesion presentation in these two dogs reveals that names of “choristoma” alone or “hamartoma” alone are not accurate to depict the continuous, composite, conjunctivo-palpebral dermoids. These cases suggest that choristoma and hamartoma might develop subsequently from the same abnormal event during the embryonic development, which means that the lesion location might be the only difference between the two terms.
机译:自收养以来,提出了两只幼犬用于评估两只眼睛的异常毛发外观。在一只狗中,损伤是对称的,并且表现为位于两个下眼睑的外侧皮肤表面上的杂乱的皮肤组织,并持续到睑板和延髓结膜,从而形成连续的损伤。在另一只狗中,右眼(OD)中存在类似的病变,但是左眼(OS)的病变是位于下眼睑和外侧结膜结膜中途的不连续,无组织的皮肤组织。手术切除病变并常规处理以进行组织病理学分析。明确的诊断是每只狗的结膜-睑皮样皮肤。皮肤样皮瘤位于眼表(角膜和/或结膜)上时,通常被认为是绒毛膜瘤(位于异常位置的正常组织),而在睑板皮肤上则被认为是错构瘤。在这两只狗中的病变表现表明,单独的“胆管瘤”或“眼瘤”的名称不能准确地描述连续的,复合的,结膜-睑膜皮样皮肤。这些情况表明,在胚胎发育过程中,同一异常事件可能会导致绒毛膜瘤和错构瘤继发,这意味着病变部位可能是这两个术语之间的唯一区别。

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