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首页> 外文期刊>Ceylon Medical Journal >Cord blood leptin levels in normal pregnancies, pregnancy induced hypertension and gestational diabetes mellitus
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Cord blood leptin levels in normal pregnancies, pregnancy induced hypertension and gestational diabetes mellitus

机译：正常妊娠，妊娠高血压病和妊娠糖尿病中的脐血瘦素水平

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Normal 0 false false false MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui) } /* Style Definitions */ table.MsoNormalTable{mso-style-name:"Table Normal";mso-tstyle-rowband-size:0;mso-tstyle-colband-size:0;mso-style-noshow:yes;mso-style-parent:"";mso-padding-alt:0cm 5.4pt 0cm 5.4pt;mso-para-margin:0cm;mso-para-margin-bottom:.0001pt;mso-pagination:widow-orphan;font-size:10.0pt;font-family:"Times New Roman";mso-ansi-language:#0400;mso-fareast-language:#0400;mso-bidi-language:#0400;} Objective To compare cord blood leptin concentrations between normal pregnancy, pregnancy induced hypertension (PIH), and gestational diabetes mellitus (GDM). Design Cross-sectional study. Setting Academic institutes and a tertiary care maternal hospital. Method 48 newborns of normal pregnancies (N=18), pregnancy induced hypertension (N=16), and gestational diabetes mellitus (N=14) were studied. Cord blood samples were collected and newborn anthropometric indices recorded at delivery. Leptin concentrations were measured using an enzyme immunoassay. Results Cord blood leptin levels were significantly different between the 3 groups (Kruskal-Wallis ANOVA; P=0.0064), and the difference resulted mainly from higher levels in GDM than in PIH [geometric mean (95% CI) for GDM: 10.89 (6.30, 18.84) vs PIH: 3.49 (2.14, 5.69) ng/ml (Dunn's multiple comparison: P Conclusion In GDM cord blood leptin levels are significantly higher, and a source other than fetal adipocytes appears to contribute to this. ? Key words: cord blood leptin, neonatal anthropometry, fetal growth, placenta doi:10.4038/cmj.v53i3.246 Ceylon Medical Journal Vol. 53, No. 3, September 2008 pp.79-82
机译：正常0否否否MicrosoftInternetExplorer4 st1 ：* {behavior：url（#ieooui）} / *样式定义* / table.MsoNormalTable {mso-style-name：“ Table Normal”; mso-tstyle-rowband-size：0; mso-tstyle-colband-size：0; mso-style-noshow：yes; mso-style-parent：“”; mso-padding-alt：0cm 5.4pt 0cm 5.4pt; mso-para-margin：0cm; mso- para-margin-bottom：.0001pt; mso分页：寡妇孤儿;字体大小：10.0pt; font-family：“ Times New Roman”; mso-ansi语言：＃0400; mso-fareast语言：＃ 0400; mso-bidi-language：＃0400;}目的比较正常妊娠，妊高征（PIH）和妊娠糖尿病（GDM）之间脐带血瘦素的浓度。设计横断面研究。设立学术机构和三级产妇医院。方法研究了48例正常妊娠（N = 18），妊娠高血压综合征（N = 16）和妊娠糖尿病（N = 14）的新生儿。收集脐带血样本，并在分娩时记录新生儿人体测量指标。使用酶免疫测定法测量瘦素浓度。结果3组之间的脐血瘦素水平存在显着差异（Kruskal-Wallis ANOVA; P = 0.0064），差异的主要原因是GDM的水平高于PIH [GDM的几何平均值（95％CI）：10.89（ vs. PIH：6.30，18.84）：3.49（2.14，5.69）ng / ml（Dunn多重比较：P结论在GDM脐带血中，瘦素水平显着升高，除胎儿脂肪细胞外的其他来源似乎也有助于此。脐带血瘦素，新生儿人体测量学，胎儿生长，胎盘doi：10.4038 / cmj.v53i3.246 Ceylon Medical Journal第53卷，第3期，2008年9月，第79-82页

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