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Extramedullary relapse of IgA-lambda myeloma after recent bortezomib therapy: a case report

机译:最近的硼替佐米治疗后IgA-lambda骨髓瘤的髓外复发:一例报告

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Intracranial plasmacytomas are an uncommon presentation of extramedullary relapse of multiple myeloma. The optimal management of extramedullary plasmacytomas remains unclear, with initial reports of bortezomib showing promising clinical results. We describe a case of multiple extracellular, including intracranial, plasmacytoma, with no evidence of marrow involvement, in a patient with relapsed IgA multiple myeloma. To our knowledge, this is the first reported case of a patient with rapid extramedullary relapse of disease despite recent exposure to bortezomib and dexamethasone.
机译:颅内浆细胞瘤是多发性骨髓瘤髓外复发的罕见表现。尚无关于髓外浆细胞瘤的最佳治疗方法,硼替佐米的初步报道显示有希望的临床结果。 IgA多发性骨髓瘤复发的患者中,我们描述了多发性细胞外(包括颅内,浆细胞瘤)病例,无骨髓累及迹象。据我们所知,这是首次报告的病例,尽管最近接触了硼替佐米和地塞米松,但该疾病仍迅速发生了髓外复发。

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