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Nadroparine-induced skin necrosis on a patient with essential thrombocythaemia: a case report

机译：Nadroparine诱发原发性血小板增多症患者的皮肤坏死：一例报告

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摘要

Skin necrosis is a rare but serious complication of subcutaneously administered low-molecular-weight heparin. We report a case of a 53-year-old female patient with skin necrosis induced by subcutaneous administration of nadroparine. The patient suffered from essential thrombocythaemia on a background of chronic myeloproliferative disease. She was admitted to our clinic with a subacute ileus due to endometriosis of the rectosigmoid junction. She underwent a high anterior resection and she received pre- and postoperative antithrombotic prophylaxis with subcutaneous nadroparine on a daily basis. On the 6th and 7th postoperative days, two skin necroses occurred at two injection sites.
机译：皮肤坏死是皮下给予低分子量肝素的罕见但严重的并发症。我们报告了一例53岁女性患者的皮下注射萘达帕林引起的皮肤坏死。该患者在慢性骨髓增生性疾病的背景下患有原发性血小板增多症。由于直肠乙状结肠连接处子宫内膜异位，她因亚急性肠梗阻而入院。她接受了高度的前切除术，并且每天接受皮下注射萘达莫林的术前和术后抗血栓预防。术后第6天和第7天，在两个注射部位发生了两次皮肤坏死。

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