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中国烧伤创疡杂志

中国烧伤创疡杂志

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The Chinese Journal of Burns Wounds And Surface Ulcers
本刊内容新颖，结构规范，涉及面广，实用性强，普及与提高兼顾，基础与临床并重，在国内外有着广泛地影响，是医药卫生核心期刊之一。
  • 发文量：2402
  • 被引量：428
  • H指数：1
  • 开始收录时间：1989(1)
  • CNKI综合因子：0.847
  • 维普期刊影响因子： 1.23
  • 万方期刊影响因子：1.1
  • 创刊时间：1989
  • 国内刊号/CN：11-2650/R
    国际刊号/ISSN：1001-0726
  • 发行周期：双月刊
    邮发代号：82-600
  • 主管单位：中华人民共和国卫生部
    主办单位：中国医师协会
中国烧伤创疡杂志-联系信息
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  • 电话：010-58701592
  • 邮箱：periodical@chinaburn.com
  • 地址：北京市朝阳区东大桥路8号尚都国际中心A座31层
  • 邮编：100020
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中国烧伤创疡杂志 >2023年第5期

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  • 摘要：目的 探索原位再生医疗技术(MEBT/MEBO)治疗慢性难愈性创面的治疗特点及临床疗效.方法 52例慢性难愈性创面患者在治疗基础疾病的同时局部采用MEBT/MEBO治疗；无法自愈的创面,查找病因,彻底清除病灶,待肉芽组织培养成熟后行植皮等手术治疗；动态监测创面分泌物的培养及药敏试验结果,并根据培养及药敏试验结果针对性用药;观察、分析治疗效果.结果 52例患者经MEBT/MEBO治疗后感染得到有效控制,创面完全愈合时间为99.83 d±35.44 d(30 d～180 d),其中31例患者通过湿润烧伤膏(MEBO)换药治疗后创面自行愈合；2例患者在MEBO换药治疗后,行Ⅱ期手术缝合处理,创面愈合；2例患者创面通过邻近皮瓣推进手术修复;2例糖尿病足并发足趾坏疽患者接受截趾手术,术后创面愈合良好；其余15例患者共行20次植皮手术后创面愈合.随访1年发现,所有植皮创面的皮下组织饱满均匀,部分愈后皮肤散在色素沉着,皮肤质地柔软,延展性好,无明显增生性瘢痕,无溃疡复发；2例皮肤溃疡恶变患者,愈合后分别随访1年和4年,均未见肿瘤复发.结论 MEBT/MEBO可抑制定植致病菌、耐药菌生长,控制创面感染,促进创面愈合,使愈后创面更自然、美观,为慢性难愈性创面的治疗提供了可靠的治疗方法.
  • 摘要：目的 探讨重组人粒细胞巨噬细胞集落刺激因子(rhGM-CSF)凝胶在Ⅱ～Ⅲ度压疮创面治疗和护理中的临床应用效果.方法 将85例(98处)Ⅱ～Ⅲ度压疮患者分为两组,试验组创面应用重组人粒细胞巨噬细胞集落刺激因子凝胶治疗,对照组创面应用磺胺嘧啶银(SD-Ag)霜治疗,观察、对比两组患者治疗效果、创面细菌培养及PUSH评分结果.结果 试验组平均愈合时间为16.75 d±l.22d,有效率为96.49％,对照组平均愈合时间为21.73 d±4.55 d,有效率为78.05％.换药14 d后,试验组患者创面PUSH评分为5.76±2.59,对照组为8.59±3.23,各项指标对比,差异均具有统计学意义(P＜0.01).结论 重组人粒细胞巨噬细胞集落刺激因子凝胶能抑制Ⅱ～Ⅲ度压疮创面细菌繁殖,促进肉芽组织生成,显著缩短创面愈合时间.
  • 摘要：目的 观察、探讨湿润烧伤膏(MEBO)治疗婴儿皮肤褶烂的临床疗效.方法 对18例患儿皮损创面采用MEBO换药治疗,每日1～2次,观察创面愈合情况.结果 18例患儿褶烂局部皮肤红斑、水肿均于治疗24 h后明显减轻,渗出明显减少；平均治疗2.8d后,皮损局部红斑、肿胀、渗出全部消退,糜烂创面愈合.结论 采用MEBO治疗婴儿皮肤褶烂,愈合快、疗效好、操作简便,值得临床推广应用.
  • 摘要：广西省武宣县中医院是全国二级甲等中医医院，也是武宣县医疗保险、新农合及城镇居民医疗保险定点医院，中国糖尿病综合防治计划推广定点医院。在职职工223人，开设床位118张，年门诊患者数13万余人次，年住院患者数9000余人次，手术患者1000余例，院内设有内科、儿科、妇产科、骨伤科、外科、急诊科、康复科等19个临床科室。
  • 摘要：《中国药物评价》杂志(ISSN2095-3593、CN10-1056/R)由国家食品药品监督管理总局主管、国家食品药品监督管理局信息中心主办的医药科技期刊,致力于上市药物的评价研究,旨在加强用药安全和合理用药指导,为药品使用和监督决策提供参考。读者对象为一线临床医师、药师,医药科研、生产、经营、教育、服务机构的专业人士,以及各级药品监管、医药卫生、医药行业管理、社会保障等政府部门的人员。主要栏目有:药物管理(包括证据与决策、药物研究的伦理与科学、警戒与通报)、药品评价(包括基础研究、临床研究、循证医学评价。
  • 摘要：目的：对比观察原位再生医疗技术（ MEBT/MEBO）和磺胺嘧啶银锌霜治疗Ⅲ期褥疮的临床效果。方法将46例Ⅲ期褥疮患者利用随机数字表法随机分为治疗组（25例）与对照组（21例），治疗组采用原位再生医疗技术治疗，对照组采用磺胺嘧啶银锌霜治疗，观察、对比两组患者的60 d治愈率、最终自愈率、创面愈合时间、平均住院费用等。结果治疗组患者的60 d 治愈率为64.00％，最终自愈率为84.00％，无效率为8.00％，平均愈合时间为57.06 d ±10.18 d，平均住院费用为2.81万元±0.35万元。对照组患者的60 d治愈率为38.10％，最终自愈率为66.70％，无效率为14.20％，平均愈合时间为74.62 d ±11.23 d，平均住院费用为3.75万元±0.46万元。结论原位再生医疗技术更有利于Ⅲ期褥疮创面愈合，可缩短住院时间，降低治疗费用，是治疗褥疮的有效方法，值得临床推广应用。%Objective To observe comparatively the clinical results of treating stage Ⅲ bedsores with MEBT/MEBO and sulfadiazine zinc silver cream respectively. Method A total of 46 patients with stageⅢbedsores were divided into treatment group ( 25 ) and control group ( 21 ) based on random number table. The treatment group adopted MEBT/MEBO treatment while the control group received the sulfadiazine zinc silver cream. The healing rate in 60 days, ultimate self-healing rate, wound healing time and average hospitalization expenses for both broups were observed and compared. Re-sult For treatment group, the healing rate in 60 days was 64.00%, the ultimate self-healing rate was 84.00%, the inef-fective ratewas 8.00%, the average healing time was 57.06 d ± 10.18 d and the average hospitalization expense was 28, 100 ± 3, 500 yuan. And, the same figures for control group were respectively 38.10%, 66.70%, 14.20%, 74.62 d ± 11.23 d and 37,500 ±4,600 yuan. Conclusion In-situ regenerative medical technology (MEBT/MEBO) is more condu-cive to wound healing of stage Ⅲ bedsores, shortening the hospitalization time and reducing the treatment cost. It is an ef-fective means to treat bedsores, being worthy of clinical promotion and application.
  • 摘要：Objective To observe the clinical effect of MEBO on fat liquefaction in treatment of postoperative in-cision of Cesarean section through comparative study. Method Sixty eight patients with obesity and fat liquefaction in post-operative incision of Cesarean section were randomly divided into Treatment Group (34 cases) and Control Group (34 ca-ses) . Patients in Treatment Group received MEBO dressing treatment for their postoperative incisions; those in Control Group adopted conventional dressing therapy. Results of both groups were observed and compared. Result The t and χ2 tests were adopted to compare the durations of treatment and incision healing, grade A healing rate of incisions and satisfac-tory level of patients to the healing of incisions. The differences had statistical significance (P<0�05, P<0�01). Conclu-sion In treatment of fat liquefaction of postoperative incision of Cesarean section, MEBO can shorten healing time, in-crease grade A healing rate of incisions and improve healing quality of skin, as well as has the feature of easy and convenient to operate, being worthy of clinical promotion.%目的：通过对照研究，观察湿润烧伤膏（ MEBO）治疗剖宫产术后切口脂肪液化的临床疗效。方法将68例肥胖型剖宫产术后切口脂肪液化患者随机分为治疗组（34例）与对照组（34例）。治疗组患者术后切口采用MEBO换药治疗，对照组患者术后切口采用常规换药治疗，观察、对比两组患者的治疗效果。结果两组患者治疗时间、切口愈合时间、切口甲级愈合率、患者对愈合切口满意度的比较，采用t检验和χ2检验，差异具有统计学意义（P＜0�05， P＜0�01）。结论 MEBO治疗剖宫产术后切口脂肪液化，可缩短愈合时间，增加切口甲级愈合率，提高皮肤愈合质量，且操作简单，使用方便，值得临床推广应用。
  • 摘要：Objective To explore the means and efficacy of delayed resuscitation in patients with extensive burns. Method The fluid resuscitation plan for shock stage of burns provided by the 107th Hospital of PLA (hereinafter referred to as 107 Resuscitation Plan) was adopted as the resuscitation treatment in 25 patients with extensive burns and at delayed admission, and the efficacy was observed. Result Twenty three patients were all healed and discharged, two patients died from multi-organ failure 6 days and 34 days after injury respectively. Conclusion The 107 Resuscitation Plan can help es-timate the accumulated loss of fluid and transfusion speed. It can be used in patients who were at shock stage and delayed to be hospitalized.%目的：探讨大面积烧伤患者延迟复苏的方法及其疗效。方法采用中国人民解放军第107医院提出的烧伤休克期液体复苏方案（下称“107复苏方案”）对25例延迟入院的大面积烧伤患者进行复苏治疗，观察治疗效果。结果23例患者痊愈出院，2例患者分别于伤后第6天和第34天死于多器官功能衰竭。结论107复苏方案能够预估累积丢失量和输液速度，可用于延迟入院治疗的烧伤休克期患者。
  • 摘要：目的：观察、总结原位再生医疗技术（ MEBT/MEBO）治疗大面积颅骨外露创面的临床疗效。方法对16例大面积颅骨外露患者创面全程应用原位再生医疗技术治疗，观察治疗效果。结果16例患者创面全部愈合，愈合时间为26～91 d，愈后创面无畸形及明显瘢痕，功能恢复良好。结论原位再生医疗技术治疗大面积颅骨外露创面，疗效显著，方法简便，值得临床推广应用。%Objective To observe and summarize the clinical curative efficacy of MEBT/MEBO in treatment of wounds with extensive skull exposure. Method Sixteen patients with extensive skull exposure wounds received full course of MEBT/MEBO treatment, and the therapeutical efficacy was observed. Result All wounds of the 16 patients healed with-in 26 to 91 days, leaving no malformations or obvious scars and achieving satisfactory recovery of functions. Conclusion MEBT/MEBO is effective and easy to operate in treatment of wounds with extensive skull exposure, being worthy of being promoted clinically.
  • 摘要：Objective To summarize the nursing experiences in the treatment of radiodermatitis with MEBO. Method Comprehensive measures including fundamental care, psychological care, skin and wound care were provided ac-tively in MEBO treatment of patients with radiodermatitis. The outcomes of treatment and nursing were observed. Result All patients’ wounds healed satisfactorily through careful and patient treatment and nursing No scar or disfunction was left. Conclu-sion Comprehensive care carried out at the same time of treating radiodermatitis with MEBO is easy to operate, effective and free from side effects. It dose not influence the treatment of underlying disease, worth being promoted and applied clinically.%目的：总结MEBO治疗放射性皮炎的护理经验。方法在对放射性皮炎患者采用MEBO治疗的过程中，积极采取基础护理、心理护理、皮肤护理、创面护理等综合护理措施，观察治疗及护理效果。结果通过细致耐心的治疗与护理，所有患者创面均愈合良好，愈后无瘢痕，无功能障碍。结论在采用MEBO治疗放射性皮炎的同时予以综合护理，方法简便，疗效显著且无副作用，不影响其基础疾病的治疗，值得临床推广应用。
  • 摘要：Objective To investigate the influence of endotoxins in serum of burn patients on 4 inflammatory cyto-kines in peripheral blood mononuclear cells of a normal person. Method The peripheral blood mononuclear cells of a nor-mal person were used as subjects for test and the serum of burn patients was used as a stimulus. According to the level of endotoxins contained in their serum, 18 burn patients and 6 healthy volunteers were divided into control group ( 6 healthy volunteers with a serum endotoxin level of 0 U/mL), test group A (6 burn patients with a serum endotoxin level of 0~0�2 U/mL), test group B (6 burn patients with a serum endotoxin level of 0�2~0�4 U/mL), and test group C (6 burn patients with a serum endotoxin level of over 0�4 U/mL) . The serum of all four groups were used respectively to stimulate PBMCs in cell culture for different length of time, after which the concentrations of TNF-α, IL-1β, IL-6 and IL-12 in supernatant of the cell culture of each group were determined by radioimmunoassay and data analysis was conducted. Result TNF-a and IL-6 increased remarkably after being stimulated by endotoxins of various concentrations for various length of time. IL-1βand IL-12 increased greatly only after prolonging the stimulating time. Conclusion TNF-a and IL-6 are two major inflam-matory media in endotoxin induced burn inflammation, their concentrations can increase with the prolonging of time or the increase of endotoxin’ s concentration. However, the concentrations of IL-1βand IL-12 do not change along with the change of endotoxin concentration, they increase gradually along with the prolonging of stimulating time.%目的：探讨烧伤患者血清内毒素对正常机体外周血单个核细胞（ peripheral blood mononuclear cells， PBMCs）中4种炎性细胞因子的影响。方法以正常人外周血单个核细胞为受试对象，以烧伤患者血清为刺激因素。根据18例烧伤患者与6名健康志愿者血清内毒素水平将其分为对照组（6名健康志愿者，血清内毒素为0 U/mL）、实验组A （6例烧伤患者，血清内毒素为0～0�2 U/mL）、实验组B （6例烧伤患者，血清内毒素为0�2～0�4 U/mL）、实验组C （6例烧伤患者，血清内毒素＞0�4 U/mL）。用4组血清分别刺激正常人PBMCs不同时间后，用放射免疫分析法测定每组细胞培养上清液中的肿瘤坏死因子（ tumor necrosis factor， TNF）-α、白细胞介素（ interleukin， IL）-1β、 IL-6及IL-12的浓度，并进行数据分析。结果 TNF-α和IL-6在不同时间，被不同浓度血清内毒素刺激后均显著增加；随着刺激时间的延长， IL-1β和IL-12才显著增加。结论 TNF-α和IL-6为内毒素介导的烧伤炎症中重要的炎性介质，其浓度可随着时间的延长或内毒素浓度的升高而增加，但IL-1β和IL-12的浓度不随内毒素剂量的变化而变化，而是随着刺激时间的延长逐渐增加。
  • 摘要：Objective To explore the method and curative efficacy of shank perforator flap in treatment of deep pretibial burn wounds. Method Shank perforator flaps of 9 cm × 3 cm~16 cm × 12 cm size on inner side, front outer side, back outer side and back side were adopted to repair 50 cases of deep pretibial burn wounds measured 7 cm × 2 cm~13 cm × 10 cm. The treatment effects were observed. Result All flaps well survived after skin grafting, except that top flap necrotized in three patients. In follow-up visits six months to one year after surgery all diseased limbs were free from disfunc-tion and the appearance and quality of flap were good. Conclusion Shank perforator flaps enjoy reliable blood supply and convenient operation with good postoperative restoration of appearance and function of wounds, being an effective and safe means of repairing pretibial deep wounds.%目的：探讨小腿穿支皮瓣修复胫前深度烧伤创面的方法及疗效。方法采用小腿内侧、前外侧、后外侧及后侧面积为9 cm ×3 cm～16 cm ×12 cm的穿支皮瓣修复50例面积为7 cm ×2 cm～13 cm ×10 cm的胫前深度烧伤创面，观察治疗效果。结果除3例患者植皮后创面出现皮瓣尖端坏死外，其余皮瓣均成活良好；术后随访6个月～1年，所有患肢均无功能障碍，皮瓣外观和质地良好。结论小腿穿支皮瓣血供可靠，手术操作简便，术后创面外形、功能恢复良好，是胫前深度烧伤创面安全、有效的修复方法。
  • 摘要：目的：克隆铜绿假单胞菌外膜蛋白OprH基因，构建其原核表达载体并鉴定其表达。方法从铜绿假单胞菌中提取基因组DNA进行PCR扩增OprH基因；采用T-A克隆技术构建pMD19T-OprH重组质粒，并经酶切和序列测定后，获得OprH片段插入到原核表达载体pET28b中，以构建pET28b-OprH重组表达质粒，并在表达宿主菌E�Coli BL21中经IPTG诱导表达及通过SDS-PAGE电泳鉴定。结果 pET28b-OprH原核表达载体构建成功；重组表达质粒经IPTG诱导后表达外膜蛋白OprH。结论成功克隆了OprH基因并获得原核表达物，为进一步研究快速检测该菌的方法奠定了基础。%Objective To clone the gene of outer membrane protein OprH of Pseudomonas aeruginosa ( PA) , construct a prokaryotic expression vector and identify its expression. Method The DNA genome was extracted from PA, the OprH gene was amplified by primers of PCR. The recombinant plasmid pMD19T-OprH was constructed by using T-A cloning. After enzyme digestion and sequence analysis, the OprH gene was inserted into prokaryotic expression vector pET28b to construct recombinant expression plasmid pET28b-oprH, which was expressed in E. coli BL21 (DE3) cells with induction by IPTG. Then the expressed protein was analyzed by SDS-PAGE. Result Construction of the prokaryotic ex-pression vector pET28b-oprH was successful. Then the recombinant expression plasmid expressed a corresponding protein OprH after being induced by IPTG. Conclusion OprH gene was successfully cloned and the prokaryotic expression product was obtained. It provides the basis for investigating a method of rapid detection of PA.
  • 摘要：目的：探讨湿润烧伤膏（ MEBO）治疗日光性皮炎的临床疗效。方法将240例日光性皮炎患者分为治疗组（120例）与对照组（120例），两组患者均口服西替利嗪，每日1次，每次10 mg。治疗组创面局部应用MEBO暴露治疗，对照组创面应用复方炉甘石洗剂治疗，对比观察两组患者的有效率、感染率及治愈时间。结果治疗组患者有效率明显高于对照组（P＜0�01），感染率明显低于对照组（P＜0�01），治愈时间明显短于对照组（P＜0�01）。结论 MEBO治疗日光性皮炎的疗效优于复方炉甘石洗剂，适用于海上群体日光性皮炎的治疗。%Objective To explore the clinical efficacy of MEBO in treating solar dermatitis. Method A total of 240 patients with solar dermatitis were divided into two groups, the treatment group (120) and control group (120), which orally took Cetirizine once a day at the dosage of 10 mg. The wounds in treatment group received exposed therapy of MEBO, and the control group was treated with compound calamine lotion. The effective rate, infection rate and healing time of the two groups were observed and compared. Result Compared to control group, patients in treatment group had obviously higher effective rate (P<0�01), lower infection rate (P<0�01), and shorter healing time (P<0�01). Conclusion MEBO is superior to compound calamine lotion in treating solar dermatitis, being suitable for treatment of offshore mass solar dermatitis.
  • 摘要：《中国烧伤创疡杂志》于1989年创刊。是由卫生部主管，中国医师协会主办的国家级医学学术期刊。本刊内容新颖．结构规范，涉及面广，实用性强；普及与提高兼顾，基础与临床并重，可供从事烧伤、创伤、溃疡、整形、美容及相关学科的各级临床、教学和科研人员及医学院校学生阅读参考。本刊是双月刊，CN11-2650／R，ISSN 1001-0726。邮发代号：82-600。
  • 摘要：我们的人体再生生命科学已经研究发展了20余年，如今它将要进入一个新的阶段--人体再生生命启动阶段。现在，在世界这个大科学舞台上，只剩下我们的科学在独自发展，而它所达到的高度，大家都很清楚。但是，它是如何发展的，未来又该向哪个方向发展，今天将要给大家进行详细讲解。可以说，接下来的发展对于我们的科学来说是一个非常重要的里程碑式的转折。今天讲座的题目是人体再生生命启动计划，主要内容是归纳如何直接应用人体再生生命科学。
  • 摘要：摘要是对一篇论文的总结，是对论著清楚、精确的概括。为了便于进行国际学术交流。本刊论著类文章所附的中英文摘要用的是国际通用的结构式摘要。中文摘要和英文摘要的字数原则上不限．在保证充足信息量的前提下，尽量简化叙述。结构式摘要分“目的”、“方法”、“结果”、“结论”四部分，现将各部分的撰写要求分述如下：
  • 摘要：“2014全国医药卫生期刊学术研讨会暨全国医药卫生期刊编辑伦理培训班”于4月11—14日在上海成功举办。本次研讨会与培训班由中国期刊协会医药卫生期刊分会、中华医学会杂志社联合主办，中国全科医学杂志社承办，中国健康教育中心／卫生部新闻宣传中心、中国高校科技期刊研究会、上海市科技期刊学会医学工作委员会支持。国内外专家及各期刊代表共204人参会，其中有160余家期刊社、编辑部参加了研讨会暨培训班。
  • 摘要：为适应新媒体形势需要，《中国烧伤创疡杂志》编辑部建立了远程稿件处理系统，于2012年5月1日正式启用。所有的作者投稿、专家审稿、稿件处理、编辑校对、日常办公等各项工作将直接在网络上进行．．编辑部远程稿件处理系统的启用将有利于提高编辑部办公效率、节约成本、方便作者投稿、方便专家审稿、缩短审稿周期和出版周期。希望广大作者、审稿专家、读者能逐步适应这一新变化，共同尽快实现这一转变.
  • 摘要：Statistics-related problems in first drafts of medical journal contributions are summarized and the causes of absence of statistical processing, unreal statistical processing and wrong methods of statistical processing are analyzed. The authors and editors are encouraged to improve their knowledge of medical statistics, and the reviewers shall be strict in check of statistical contents from the start.%总结医学期刊初稿中存在的统计学问题，分析无统计学处理、未真正进行统计学处理和统计学方法错误出现的原因，提倡作者和编辑应加强医学统计学知识的学习，审稿人应从稿件初审阶段对统计学内容把关。
  • 摘要：目的：探讨严重胸部高压电烧伤的临床特点及皮瓣移植的治疗效果。方法对6例胸部严重高压电烧伤合并肋骨和（或）肺组织烧伤坏死的患者创面采用皮瓣转移与游离皮瓣移植术治疗，观察治疗效果。结果6例患者中有4例患者创面Ⅰ期愈合，1例患者创面因皮瓣部分缺血坏死而行二次植皮手术后Ⅱ期愈合，1例患者因术后2h病情恶化而死亡。结论皮瓣移植术是治疗严重胸部高压电烧伤创面的有效方法，成功的关键在于皮瓣的设计及手术时机的选择。%Objective To investigate the clinical characteristics of severe high voltage electric burns on chest and the treatment efficacy of skin flap transplantation. Method Six patients with severe high voltage electric burns on chest com-bined with necrotic burns of rib and ( or) pulmonary tissues were treated with flap transfer and free flap transplantation. The treatment efficacies were observed. Result Four out of six patients achieved primary healing; and secondary healing hap-pened in one patient after the second skin plantation surgery due to ischemia and necrosis of the original skin flap;one died 2 hours after surgery due to deteriorating conditions. Conclusion Skin flap transplantation is an effective means to treat severe high voltage electric burns on chest. The key to success is the design of skin flap and the selection of timing of surgery.
  • 摘要：Objective To explore effective means to treat comminuted finger injuries in an effort to maintain the length and function of fingers as most as possible. Method For the six patients with comminuted finger injuries, at the same time of carrying out systemic treatment, MEBT/MEBO combined with infrared irradiation was applied to the local wounds to observe the therapeutic effect after conservative debridement. Result The funicular tissues of 23 injured fingers of the 6 patients all survived and all wounds healed. The average hospitalization time is 14.5 days. In the follow-up visit carried out half a year later, no scars were formed on wounds, the healed fingers had senses of pain and temperature which were at a good level of functionality. Conclusion Local application of MEBT/MEBO combined with infrared irradiation af-ter conservative debridement to treat comminuted finger injuries is easy and convenient, having high success rate and being capable of effectively maintaining the length and functions of fingers. It can serve as an effective means of treatment in pa-tients with finger injuries not eligible for replantation, being worthy of clinical promotion and application.%目的：探讨治疗手指粉碎性损伤的有效方法，以期最大限度保留手指长度及其功能。方法6例手指粉碎性损伤患者在全身治疗的同时，局部创面予以保留清创后应用原位再生医疗技术（ MEBT/MEBO）结合红外线局部照射治疗，观察治疗效果。结果6例患者的23只损伤手指的条索状组织均成活，损伤创面均康复，平均住院时间为14.5 d；半年后随访，手指创面无瘢痕形成，痛、温觉存在，功能良好。结论保留清创后，局部采用MEBT/MEBO结合红外线照射治疗手指粉碎性损伤，方法简便，成功率高，可有效保留手指长度及其功能，是无再植条件的手外伤患者的有效治疗方法，值得临床推广应用。
  • 摘要：将近年来各种类型激光治疗对增生性瘢痕中Ⅰ型及Ⅲ型胶原表达与比例变化的影响及研究进展进行较为系统的分析、总结和归纳，为临床上选择有效的增生性瘢痕的治疗方案提供参考。%Systematic analysis, summary and conclusion was done in terms of the influences of various laser thera-pies on expression and ratio of collagen type Ⅰ and Ⅲ in hypertrophic scar as well as related research progress, providing reference for selecting effective therapeutic regimen of hypertrophic scars in clinic.
  • 摘要：已被公知公认的缩略语如DNA、RNA、HbsAg、CT、Ig、PCR，可不加注释直接使用。以下词汇也允许直接使用英文缩写。
  • 摘要：在开启人体再生生命计划的关键历史时期，在生命科学发展的新形势下，徐荣祥教授在第十三届全国烧伤创疡学术会议中回顾了人体再生复原科学的发展历程，讲解了人体再生复原科学（简称：器官再生科学）的核心内涵和最新学术动态，展示了人体再生复原科学的实践成果与发展方向，公布了已经取得明显再生还童效果的再生皮柱技术，该项新技术是把可吸收的再生物质导入到器官组织中，使其在局部发挥再生复原作用，进一步验证了器官再生科学可以应用于非创伤性器官的再生，从而说明了除皮肤以外的各种器官都可以在正常组织结构上再生，而非只能在缺损器官上再生。这一突破性的人体再生复原科研成果，使人类千百年来梦寐以求的再生还童梦想得以呈现。　　徐荣祥教授在演讲中还指出，人体再生复原科学已成为世界生命科学领域中唯一实现临床应用的造福于人类的前沿科学，它在给人类带来再生生命幸福生活的同时，也给人类创造了一个全新的再生生命世界。%At the critical historical stage of the plan of initiating human regenerative life and under the new developmental situation of life science, Prof. Xu Rongxiang, on the 13th Chinese Burns Wounds and Ulcers Conference, re-called the development process of Human Body Regenerative Restoration Science ( HBRRS, also called Organ Regeneration Science for short) , explained its core meaning and the latest academic development, demonstrated its practical achievements and developmental direction, and announced the regenerative skin column technology which had been applied to achieve sig-nificant effect of regenerative rejuvenation. With this new technique, absorbable regenerative substances can be introduced into tissues and organs and exert regenerative restoration function locally, further confirming that HBRRS can be applied in the regeneration of uninjured organs. And, besides skin organ, all other organs can be regenerated from normal tissues, rather than only in damaged organs. This groundbreaking scientific achievement of HBRRS helps realize the long lasting mankind's dream of regeneration and rejuvenation. Prof. Xu also pointed out in his speech that HBRRS is a cutting-edge science which is the only one accomplishing clin-ical application and benefiting the mankind in the field of world life science. It brings all human beings happy living of re-generative life and creates a brand new world of regenerative life.
  • 摘要：目的：对比观察湿润烧伤膏（MEBO）与磺胺嘧啶银（SD-Ag）治疗深Ⅱ度和Ⅲ度烧伤的临床疗效。方法将92例深Ⅱ度和Ⅲ度烧伤患者，随机分为治疗组和对照组，每组46例，治疗组采用湿润暴露疗法治疗，对照组应用磺胺嘧啶银药纱包扎治疗，对比两组患者疼痛率、感染率、手术率、瘢痕形成率及创面愈合时间。结果两组相比，治疗组疼痛发生率、瘢痕发生率、感染率及手术率均较对照组低， P＜0�05，差异具有统计学意义；治疗组创面愈合时间明显比对照组短， P＜0�05，差异具有统计学意义。结论湿润烧伤膏治疗深Ⅱ度和Ⅲ度烧伤创面具有止痛效果好、感染率低、创面愈合时间短、瘢痕形成少、无需手术等优点，是治疗深度烧伤创面的理想方法。%Objective To observe comparatively the clinical effects of MEBO and SD-Ag in treating burns of deepⅡ degree andⅢdegree. Methods The 92 patients with burns of deepⅡdegree andⅢdegree were randomly divided in-to Treatment Group and Control Group, 46 cases each. The Treatment Group is treated with exposed MEBOand Control Group with SD-Ag gauze bandaging. The ratesof pain, infection, surgery, scar formation and healing time of the wound were compared. Results The rates of pain, scar formation, infection and surgery in Treatment Group were all lower than that in Control Group, P<0�05, the difference is of statistical significance;the wound healing time in Treatment Group is obvious-ly shorter than that in Control Group, P<0�05, the difference is of statistical significance. Conclusion MEBO is satisfac-tory in treating burns of deep Ⅱ degree andⅢ degree in terms of good pain relief, low infection rate, short wound healing time, less scar formation and freedom of surgery, which is anideal method for treatment of deep burns.
  • 摘要：Objective Summarize and analyze the clinical curative effect of treating chronicskin ulcers with MEBT/MEBO combined with infrared ray. Methods Sixty patients with chronic skin ulcerwere randomly divided into ex-perimental group and control group. At thesame time of treating the primary diseases, wounds of the experimental group was giventopical MEBO treatmentcombined with infrared radiation, whilewounds ofthe control group was given only MEBO treat-ment. Wound healingin the two groups of patients was observed. Results All wounds inbothgroupshealedon their own. In the experimental group, except that the healing time was 31 daysfor a 71-year-old elderly patient due to the complicationof-systemic infection, the remaining 29 patients hadan average wound healing time of 14�3 days; the average wound healing timefor the 30 patients in the control groupwas 17�7 days. Follow-upwasconducted for 6 to 12 months, two groups of patients had no recurrence of the wound, and no statistically significant difference (P>0�01) in terms of scar formationafter heal-ing. Conclusion Infrared radiation is conducive to exerting the efficacy of MEBO. Combination of both can accelerate wound healing, worthy of clinical promotion.%目的：总结、分析烧伤湿性医疗技术（ MEBT/MEBO）结合红外线治疗慢性皮肤溃疡的临床疗效。方法将60例慢性皮肤溃疡患者随机分为实验组（30例）和对照组（30例），在治疗原发病的同时，实验组创面采用外涂湿润烧伤膏（ MEBO）结合红外线照射治疗，对照组创面单纯外用MEBO治疗，观察两组患者创面愈合情况。结果两组患者创面均自行愈合，实验组除1例71岁高龄患者因合并全身感染致使创面愈合时间长达31 d外，其余29例患者创面平均愈合时间为14�3 d；对照组30例患者创面平均愈合时间为17�7 d。随访6～12个月，两组患者创面均无复发，在愈后瘢痕生成方面也无统计学差异（ P＞0�01）。结论红外线有利于MEBO药效的发挥，两者联合应用可加速创面愈合，值得临床推广。
  • 摘要：病例1，男，2岁 因沸水烫伤21d于2012年10月12日是入院，烫伤面积为59%TBSA，均为Ⅲ度浅型。
  • 摘要：Objective Explore the effect of the combination of follicular unit transplantation andin-situ skin regen-eration technology on wound repair. Method All the 24 SD rats, ( half female and half male) , wererandomly divided into four groups ( 6 rats each group ) : experiment group A ( follicular unit transplantation group ) , experimental group B ( follicular unit transplantation combined with in-situ regeneration technology) , control groupC ( autologous micro skin par-ticle transplant group) and control group D ( autologous micro skin particle transplant combined with in-situ regeneration technology). Wound model was established in every rat and covered by MEBO gauze (group B and D) or vaseline gauze (group A and C) which was changed once aday. Five days later, granulation tissue grew on the wound. At this time, sheared the skin ofone side beardsof rats in group A and B, and separated follicleswhich were then cut into follicular units consisting of follicle papilla, surrounding tissues and some epidermal skin, and the follicular units were transplanted into the prepared wound models of their own. In group C and D, epidermis with part of dermal skin was cut from the full-thickness skin of each rat and transplanted into its own wound model. Vaseline gauzeswere used to cover the wounds in group A and C, MEBO gauzes were used to cover the wounds in group B and D. Tissue samples on wounds in all groups were taken in week 1, 2, 3, 4, 5 after operation, and histological changes were observedunder a microscope. Results The status of wound healing in group B was obviously better than group A, C and D. In view of histopathological observation, newly gen-eratedfibroblasts and capillaries in group B were morethan that in group A, C and D, and their late term decrease were more apparent. The epithelium growth and wound area decrease in group B was faster that that in group A, C and D. Conclusion MEBO can accelerate the wound healing of experimental skin ulcers in rats, by decreasing inflammatory cells, arranging the capillaries and cells in order, regulating the quantity and morphology of cells, and promoting fibroblasts producing col-lagen fibers and turning intofibrocytes thereby repairing the wounds.%目的：探讨毛囊单位移植联合原位再生技术对创面修复的作用。方法将24只SD大鼠（雌雄各半）随机分为实验组A（毛囊单位移植组）、实验组B（毛囊单位移植联合原位再生技术组）、对照组C（自体微粒皮移植组）、对照组D （自体微粒皮移植联合原位再生技术组），每组6只，制成SD大鼠体表创面模型，并在制备好的创面上分别覆盖相应的湿润烧伤膏药纱（B、 D组）及凡士林纱布（A、 C组），每天换药1次。5 d后，创面肉芽组织生长，此时剪取A、 B组大鼠的单侧鼠须垫皮肤，并分割鼠须垫毛囊，切取带有毛囊乳头、毛囊周围组织及部分表皮的毛囊单位复合组织，植入已制备好的创面中；从C、 D组大鼠的全层皮肤中切取表皮和部分真皮组织，植入已制备好的创面中； A、 C组创面覆盖凡士林纱布，B、 D组创面覆盖湿润烧伤膏药纱。分别于术后第1、2、3、4、5周取各组创面标本，镜下观察其组织学改变。结果 B组大鼠的创面愈合情况明显优于A、C、 D组，组织病理学观察可见，B组创面术后成纤维细胞及新生毛细血管的数量均多于A、 C、 D组，且其后期减少较明显； B组创面上皮组织生长速度及创面缩小速度均较A、 C、 D组快。结论湿润烧伤膏能加速实验性大鼠皮肤溃疡创面的愈合，使炎症细胞不断减少，毛细血管和细胞排列有序，调节细胞的数量和形态，促进成纤维细胞逐渐产生胶原纤维，转变成纤维细胞，从而修复创面。

    中国烧伤创疡杂志的期刊信息

    • 创刊时间：1989
    • 地区：CN
    • 语言：中文
    • 热门主题：中国医师协会
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    中国烧伤创疡杂志的获奖情况

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