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首页> 外文期刊>Case Reports in Endocrinology >The Coexistence of an Intrasellar Adenoma, Lymphocytic Hypophysitis, and Primary Pituitary Lymphoma in a Patient with Acromegaly
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The Coexistence of an Intrasellar Adenoma, Lymphocytic Hypophysitis, and Primary Pituitary Lymphoma in a Patient with Acromegaly

机译：肢端肥大症患者的鞍内腺瘤，淋巴细胞性垂体炎和垂体原发性淋巴瘤并存

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摘要

The concomitant presence of three histopathologically different entities in the pituitary gland is a rare occurrence. Most publications identify at least two distinct pathologies, mainly, a pituitary adenoma coexisting with a second intrasellar lesion. We present a case of a 71-year-old female referred for evaluation and treatment of acromegaly. Questioning revealed she was experiencing facial palsy, visual disturbances, and syncopal spells for several weeks. When laboratory evaluation showed elevated somatomedin (IGF-I) levels and an oral glucose tolerance test failed to demonstrate any suppression of her growth hormone (GH) values, an MRI of the pituitary revealed a sellar mass. A presumptive diagnosis of pituitary adenoma was established. The patient underwent transsphenoidal resection of the sellar mass, which proved to be a large B-cell lymphoma (Stage I-E) associated with areas of adenoma and lymphocytic hypophysitis.
机译：垂体腺中同时存在三种组织病理学上不同的实体是罕见的。大多数出版物确定至少两种不同的病理学，主要是与第二颅内病变共存的垂体腺瘤。我们介绍了一例71岁女性，用于评估和治疗肢端肥大症。询问显示她数周内出现面部麻痹，视力障碍和晕厥。当实验室评估显示生长激素（IGF-I）水平升高并且口服葡萄糖耐量试验未能证明其生长激素（GH）值受到任何抑制时，垂体MRI表现为鞍状肿块。建立了垂体腺瘤的推定诊断。该患者接受了蝶鞍肿物的蝶窦切除术，该病例被证实是与腺瘤和淋巴细胞性垂体炎相关的大型B细胞淋巴瘤（I-E期）。

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