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Axis I comorbidity in adolescent inpatients referred for treatment of substance use disorders

机译:因药物滥用而被转诊的青少年住院患者的I轴合并症

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Background To assess comorbid DSM-IV-TR Axis I disorders in adolescent inpatients referred for treatment of substance use disorders. Methods 151 patients (mean age 16.95 years, SD = 1.76; range 13 - 22) were consecutively assessed with the Composite International Diagnostic Interview (CIDI) and standardized clinical questionnaires to assess mental disorders, symptom distress, psychosocial variables and detailed aspects of drug use. A consecutively referred subgroup of these 151 patients consisting of 65 underage patients (mean age 16.12, SD = 1.10; range 13 - 17) was additionally assessed with the modules for attention-deficit/hyperactivity disorder (ADHD) and conduct disorder (CD) using The Schedule for Affective Disorders and Schizophrenia for school-aged children (K-SADS-PL). Results 128 (84.8%) of the 151 patients were dependent on at least one substance, the remaining patients fulfilled diagnostic criteria for abuse only. 40.5% of the participants fulfilled criteria for at least one comorbid present Axis I disorder other than substance use disorders (67.7% in the subgroup additionally interviewed with the K-SADS-PL). High prevalences of present mood disorder (19.2%), somatoform disorders (9.3%), and anxiety disorders (22.5%) were found. The 37 female participants showed a significantly higher risk for lifetime comorbid disorders; the gender difference was significantly pronounced for anxiety and somatoform disorders. Data from the underage subgroup revealed a high prevalence for present CD (41.5%). 33% of the 106 patients (total group) who were within the mandatory school age had not attended school for at least a two-month period prior to admission. In addition, 51.4% had been temporarily expelled from school at least once. Conclusions The present data validates previous findings of high psychiatric comorbidity in adolescent patients with substance use disorders. The high rates of school refusal and conduct disorder indicate the severity of psychosocial impairment.
机译:背景技术为评估转介治疗药物滥用疾病的青少年住院患者的DSM-IV-TR轴I合并症。方法151名患者(平均年龄16.95岁,SD = 1.76;范围13-22)连续接受综合国际诊断访谈(CIDI)和标准化临床问卷调查,以评估精神障碍,症状困扰,社会心理变量和药物使用的详细方面。这151名患者的连续转诊亚组由65名未成年患者组成(平均年龄16.12,SD = 1.10;范围13-17),另外使用注意力缺陷/多动障碍(ADHD)和行为障碍(CD)模块进行评估学龄儿童情感障碍和精神分裂症时间表(K-SADS-PL)。结果151例患者中有128例(84.8%)依赖于至少一种物质,其余患者仅满足滥用的诊断标准。 40.5%的参与者满足了至少一种除药物滥用疾病以外的目前并存的Axis I疾病的标准(在接受过K-SADS-PL采访的亚组中,这一比例为67.7%)。发现当前情绪障碍(19.2%),躯体形式障碍(9.3%)和焦虑症(22.5%)的患病率很高。 37名女性参与者表现出终生合并症的高得多的风险;焦虑和躯体形式障碍的性别差异显着。未成年亚组的数据显示,目前的CD患病率很高(41.5%)。在入学之前至少两个月的时间内,在106岁处于强制入学年龄的患者(总计)中,有33%没有上学。此外,至少有51.4%的学生被暂时开除学校。结论本数据证实了先前在药物滥用障碍青少年患者中高度精神病合并症的发现。学校拒绝和品行障碍的高发生率表明心理社会损害的严重性。

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