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Chronic Kidney Disease—Effect of Oxidative Stress

机译:慢性肾脏病—氧化应激的影响

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Chronic kidney disease (CKD) is a growing health problem with increasing incidence. The annual mortality of end-stage renal disease patients is about 9%, which is 10–20 fold higher than the general population, approximately 50% of these deaths are due to cardiovascular (CV) disease. CV risk factors, such as diabetes, hypertension, and hyperlipidemia, are strongly associated with poor outcome. Many other nontraditional risk factors such as inflammation, infection, oxidative stress, anemia, and malnutrition are also present. In this review we will focus on the role of oxidative stress in chronic kidney disease.
机译:慢性肾脏病(CKD)是一个日益严重的健康问题,其发病率也在增加。终末期肾病患者的年死亡率约为9%,是普通人群的10-20倍,其中约50%的死亡是由于心血管疾病引起的。心血管疾病的危险因素,例如糖尿病,高血压和高脂血症,与不良预后密切相关。还存在许多其他非传统风险因素,例如炎症,感染,氧化应激,贫血和营养不良。在这篇综述中,我们将重点研究氧化应激在慢性肾脏疾病中的作用。

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