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首页> 外文期刊>Circulation journal >Effect of Elapsed Time From Coronary Angiography Until Off-Pump Coronary Artery Bypass Surgery on Postoperative Renal Function
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Effect of Elapsed Time From Coronary Angiography Until Off-Pump Coronary Artery Bypass Surgery on Postoperative Renal Function

机译：从冠状动脉造影到非体外循环冠状动脉搭桥手术过去的时间对术后肾功能的影响

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Background: ?A new concern in acute kidney injury (AKI) following coronary artery bypass grafting (CABG) is the elapsed time from coronary angiography (CAG) until subsequent surgery. This study aimed to retrospectively evaluate renal function following elective off-pump CABG (OPCAB). Methods and Results: ?Three hundred and seven patients were divided either into group A (elapsed time between CAG and surgery ≤5 days, n=138) or B (elapsed time >5 days, n=169). The estimated glomerular filtration rate (eGFR) was obtained on the 1st, 3rd and 7th day following CABG. The pre-, intra-and postoperative relevant data were analyzed. 51 patients (16.6%) developed postoperative AKI. Patients with shorter elapsed time were more likely to present postoperative AKI than those with a longer elapsed time (23.9% vs. 10.7%, P=0.003). Multivariate logistic regression analysis showed that elapsed time had an independent influence on the development of postoperative AKI (odds ratio 2.35, 95% confidence interval 1.45–5.26, P=0.009). The eGFR reduced gradually after surgery, dropped to a minimum within 3 days, and then increased slowly in both groups. Minimum eGFR following surgery in group B was significantly higher than that in group A (64.3±6.5ml/min vs. 59.2±9.3ml/min, P
机译：背景：？冠状动脉搭桥术（CABG）后发生的急性肾损伤（AKI）的新问题是从冠状动脉造影（CAG）到后续手术所经历的时间。这项研究旨在回顾性评估选择性非体外循环CABG（OPCAB）后的肾功能。方法和结果：307例患者分为A组（CAG和手术之间的间隔时间≤5天，n = 138）或B组（经历时间> 5天，n = 169）。估计的肾小球滤过率（eGFR）在CABG后的第1、3和7天获得。分析了术前，术中和术后的相关数据。 51例患者（16.6％）发生了术后AKI。经过时间较短的患者比经过时间较长的患者更有可能出现术后AKI（23.9％vs. 10.7％，P = 0.003）。多元logistic回归分析显示，经过时间对术后AKI的发生有独立的影响（赔率2.35，95％置信区间1.45-5.26，P = 0.009）。术后eGFR逐渐降低，三天内降至最低，然后两组缓慢升高。 B组术后最低eGFR显着高于A组（64.3±6.5ml / min对59.2±9.3ml / min，P

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