首页> 外文期刊>Circulation journal >Change of Coronary Flow by Continuous-Flow Left Ventricular Assist Device With Cardiac Beat Synchronizing System (Native Heart Load Control System) in Acute Ischemic Heart Failure Model
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Change of Coronary Flow by Continuous-Flow Left Ventricular Assist Device With Cardiac Beat Synchronizing System (Native Heart Load Control System) in Acute Ischemic Heart Failure Model

机译:急性缺血性心力衰竭模型中带有心脏搏动同步系统(本机心负荷控制系统)的连续流左心室辅助装置对冠状动脉血流的变化

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Background: ?A novel control system for the EVAHEART left ventricular assist device (LVAD), known as the Native Heart Load Control System (NHLCS), can change the device’s rotational speed (RS) in synchrony with the heartbeat. The system enhanced coronary flow (CoF) with the counter-pulse mode in normal goats’ hearts, so we examined the change in CoF in goats with acute ischemic heart failure (HF). Methods and Results: ?We studied 14 goats (56.1±6.9kg) with acute ischemic HF induced by coronary microsphere embolization. We installed EVAHEART and ran the device in 4 modes [continuous support, circuit-clamp, counter-pulse (raise RS in diastole), and co-pulse (raise RS in systole)] with 50% or 100% bypass in each mode. In comparison with the circuit-clamp mode, CoF was 121.0±14.1% in the counter-pulse mode and 102.9±7.9% in the co-pulse mode, whereas it was 113.5±10.6% in the continuous mode, with 100% bypass (P
机译:背景:?一种用于EVAHEART左心室辅助设备(LVAD)的新颖控制系统,即本机心脏负荷控制系统(NHLCS),可以与心跳同步地更改设备的转速(RS)。该系统通过反脉冲模式增强了正常山羊心脏中的冠脉血流(CoF),因此我们研究了急性缺血性心力衰竭(HF)山羊中CoF的变化。方法和结果:我们研究了14只山羊(56.1±6.9kg),由冠状动脉微球栓塞引起的急性缺血性心衰。我们安装了EVAHEART,并以4种模式(连续支持,电路钳位,反脉冲(舒张压提高RS)和同脉冲(收缩压提高RS))运行该设备,每种模式均旁路50%或100%。与电路钳位模式相比,反脉冲模式下的CoF为121.0±14.1%,同脉冲模式下的CoF为102.9±7.9%,而连续模式下的CoF为113.5±10.6%,具有100%的旁路( P

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