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首页> 外文期刊>Circulation journal >Does Age at Operation Influence the Short- and Long-Term Outcomes of Off-Pump Coronary Artery Bypass Grafting?
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Does Age at Operation Influence the Short- and Long-Term Outcomes of Off-Pump Coronary Artery Bypass Grafting?

机译：手术年龄会影响非体外循环冠状动脉旁路移植术的短期和长期结果吗？

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Background: To investigate the relationship between age and both short- and long-term outcomes of off-pump coronary bypass grafting (OPCAB). Methods?and?Results: The 780 patients undergoing OPCAB were divided into 3 groups: 262 aged 75 years (late elderly), and retrospectively analyzed. The follow-up rate was 94.9%, and mean follow-up period was 5.6±3.4 years. In-hospital mortality rates were similar among the groups (0.8% in young, 1.2% in early elderly, and 1.1% in late elderly; P=0.862). In logistic regression analysis, the risk factor for predicting major complications was the New York Heart Association (NYHA) classification (odds ratio: 1.555, P=0.001), and not age. The 10-year estimated rates free from cardiac death (89.6±3.2, 95.0±2.1, and 96.5±2.1%, log rank, P=0.16) and cardiac events (71.8±3.8, 66.8±4.3, and 59.9±7.7%, P=0.61) were not significantly different among the groups. In multivariate Cox models, independent risk factors predicting cardiac events were the NYHA classification (hazard ratio (HR): 1.265, P=0.009), and ejection fraction (HR: 0.986, P=0.016), but not age (young HR: 1.0, early elderly HR: 1.276; P=0.210, late elderly HR: 0.910; P=0.707). Conclusions: Both short- and long-term cardiac outcomes of OPCAB are not influenced by age at operation. ( Circ J 2015; 79: 2177–2185)
机译：背景：探讨年龄与非体外循环冠状动脉搭桥术（OPCAB）的短期和长期结果之间的关系。方法与结果：将780例OPCAB患者分为3组：262例75岁（高龄），并进行回顾性分析。随访率为94.9％，平均随访时间为5.6±3。4年。各组的院内死亡率相似（年轻人为0.8％，早期老年人为1.2％，晚期老年人为1.1％; P = 0.862）。在逻辑回归分析中，预测主要并发症的危险因素是纽约心脏协会（NYHA）分类（赔率：1.555，P = 0.001），而不是年龄。估计的10年无心源性死亡发生率（89.6±3.2、95.0±2.1和96.5±2.1％，对数秩，P = 0.16）和心脏事件（71.8±3.8、66.8±4.3和59.9±7.7％ P = 0.61）在各组之间无显着差异。在多变量Cox模型中，预测心脏事件的独立危险因素为NYHA分类（危险比（HR）：1.265，P = 0.009）和射血分数（HR：0.986，P = 0.016），而不是年龄（年轻HR：1.0） ，早期老年人HR：1.276; P = 0.210;晚期老年人HR：0.910; P = 0.707）。结论：OPCAB的短期和长期心脏结局均不受手术年龄的影响。 （Circ J 2015; 79：2177-2185）

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