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首页> 外文期刊>Case Reports in Neurology >Trigeminal Neuralgia as the First Clinical Manifestation of Anti-Hu Paraneoplastic Syndrome Induced by a Borderline Ovarian Mucinous Tumor
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Trigeminal Neuralgia as the First Clinical Manifestation of Anti-Hu Paraneoplastic Syndrome Induced by a Borderline Ovarian Mucinous Tumor

机译：三叉神经痛是卵巢交界性黏液性肿瘤引起的抗胡副肿瘤综合征的首例临床表现

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摘要

Paraneoplastic neurologic syndrome (PNS) is an uncommon manifestation of cancer that is not caused by the tumor or metastasis. Trigeminal neuralgia (TN) is an initial symptom of this disease, but it has rarely been reported in the literature. Here, we report the case of a 76-year-old woman who presented with classic TN, followed by limbic encephalitis due to an underlying ovarian intestinal-type mucinous borderline tumor, with the presence of anti-Hu antibodies. She recovered quickly after removal of the tumor and was essentially free of symptoms 2 weeks after surgery. Because PNS precedes the tumor in approximately 60% of cases, its rapid detection and treatment are crucial. Therefore, we propose that PNS be considered during the management of TN when brain imaging is normal, as it is followed by other central and/or peripheral neurological manifestations as well as the presence of systemic symptoms such as anemia, fatigability, loss of appetite, or weight loss.
机译：副肿瘤性神经系统综合症（PNS）是癌症的罕见表现，并非由肿瘤或转移引起。三叉神经痛（TN）是该病的最初症状，但文献中很少报道。在这里，我们报道一例76岁女性，患有经典TN，随后由于潜在的肠道型粘液性交界性肿瘤而出现边缘性脑炎，并伴有抗Hu抗体。切除肿瘤后，她很快康复，术后2周基本没有症状。由于PNS在大约60％的病例中先于肿瘤，因此快速检测和治疗至关重要。因此，我们建议在脑成像正常的TN处理过程中考虑PNS，然后再进行其他中枢和/或周围神经系统表现以及诸如贫血，易疲劳性，食欲不振，或减肥。

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