Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation

ChristineKatusiime; PonsianoOcama; AndrewKambugu

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Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation

机译：表现为免疫重建炎症综合征的顽固性慢性外阴溃疡：病例观察

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HIV-1 treatment-failure patients are increasingly being initiated on second-line antiretroviral therapy. The case we describe is of a treatment-failure patient who developed intractable chronic vulval ulceration presenting as immune reconstitution inflammatory syndrome (IRIS), following complete viral suppression with second-line highly active antiretroviral treatment (HAART). To the best of our knowledge, this is the first reported case of intractable vulval ulceration IRIS in an HIV-1 treatment-failure patient.

机译：HIV-1治疗失败的患者越来越多地接受二线抗逆转录病毒治疗。我们描述的病例是治疗失败的患者，在通过二线高效抗逆转录病毒治疗（HAART）完全抑制病毒后，出现了顽固的慢性外阴溃疡，表现为免疫重建炎症综合症（IRIS）。据我们所知，这是第一例HIV-1治疗失败的患者发生顽固性外阴溃疡IRIS的病例。

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《Case Reports in Obstetrics and Gynecology》 |2011年第2期|共2页
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ChristineKatusiime; PonsianoOcama; AndrewKambugu;
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1. Chronic vulval ulceration — another immune reconstitution inflammatory syndrome? [J] . V Reddy and G A Luzzi International Journal of STD & AIDS . 2005,第6期

机译：慢性外阴溃疡-另一个免疫重建炎症综合征？
2. Chronic vulval ulceration--another immune reconstitution inflammatory syndrome? [J] . Reddy V, Luzzi GA International journal of STD & AIDS . 2005,第6期

机译：慢性外阴溃疡-另一种免疫重建炎症综合症？
3. Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study (vol 15, pg 29, 2015) [J] . Ravimohan S., Tamuhla N., Steenhoff A. P. The Lancet infectious diseases . 2015,第5期

机译：在开始抗逆转录病毒治疗的HIV感染的肺结核成年人中，与结核相关的免疫重建炎症综合征和非免疫重建炎症综合征死亡的免疫学分析：一项前瞻性观察性队列研究（2015年第15卷，第29页）
4. Inflammatory cytokines as a new targets of cardiac remodeling in patients with chronic stable angina in elderly patients [C] . Donetskya O., Tulupova V., Shuldeshova N., European Congress of Pharmacology . 2012

机译：炎症细胞因子作为老年患者慢性稳定心绞痛患者心脏重塑的新靶标
5. The Influence of Chronic Kidney Disease, Apoptosis and Inflammatory Biomarkers on the Diagnosis, Prognosis and Management of Acute Coronary Syndromes. [D] . Cardinal, Heloise. 2012

机译：慢性肾脏病，细胞凋亡和炎性生物标志物对急性冠状动脉综合征的诊断，预后和管理的影响。
6. Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation [O] . Christine Katusiime, Ponsiano Ocama, Andrew Kambugu 2011

机译：表现为免疫重建炎症综合征的顽固性慢性外阴溃疡：病例观察。
7. Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation [O] . Katusiime, Christine, Ocama, Ponsiano, Kambugu, Andrew 2011

机译：表现为免疫重建炎症综合征的顽固性慢性外阴溃疡：病例观察

Intractable Chronic Vulval Ulceration Presenting as Immune Reconstitution Inflammatory Syndrome in a Treatment-Failure Patient: A Case Observation

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