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Myometrial Cystic Formation after Local Methotrexate Application into Cornual Gestational Sac: A Case Report of an Unexpected Complication

机译:局部甲氨蝶呤应用于角膜妊娠囊后的肌层囊性形成:意外并发症的病例报告。

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Cornual pregnancy is a rare type of ectopic pregnancy, and diverse therapeutic options exist for the management. Medical treatment despite high initial beta HCG values is not thought to be safe. We reported a 39-year-old woman with an initial beta HCG value of 22000 mIU/mL and diagnosed of a cornual pregnancy. Patient was managed successfully with the administration of combined systemic and ultrasonographically guided local injection of methotrexate into the gestational sac. During followup with serial beta hcg measurements,27×20 mm cystic area in myometrium has been detected. Beta hcg <1 mIU/mL value was reached three months later, and this cystic area resolved spontaneously. Systemic methotrexate administration combined with ultrasound-guided local methotrexate injection into the gestational sac might be considered as the first-line treatment in the management of hemodynamically stable patients having cornual pregnancy even with high beta HCG values and risk of myometrial cystic formation.
机译:角膜妊娠是一种罕见的异位妊娠,存在多种治疗选择。尽管最初的βHCG值很高,但药物治疗并不安全。我们报道了一名39岁的女性,其初始βHCG值为22000 mIU / mL,并被诊断为角膜妊娠。通过全身和超声引导结合的氨甲蝶呤局部注入妊娠囊的方法成功治疗了患者。在进行连续βhcg测量的随访过程中,已检测到子宫肌层27×20 mm的囊性区域。在三个月后达到了βhcg <1 mIU / mL的值,该囊性区域自发消退。系统性甲氨蝶呤给药与超声引导下的局部氨甲蝶呤注入妊娠囊相结合,可被认为是即使角βHCG值高且有肌膜囊性增生危险的,具有角膜妊娠的血流动力学稳定患者的一线治疗。

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