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Cisplatin Therapy Does Not Worsen Renal Function in Severe Antenatal Bartter Syndrome

机译:在严重的产前肠易激综合征中,顺铂疗法不会使肾功能恶化

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A 30-year-old man with severe antenatal Bartter syndrome, diagnosed and treated in infancy, developed testicular carcinoma. Despite the known renal complications of cisplatin, this drug was used for his chemotherapy because of its superior antineoplastic effect. Nonsteroidal anti-inflammatory drug administration was continued during cisplatin therapy. Despite an increase in his oral potassium requirement, renal function was maintained following completion of chemotherapy. In spite of its significant associated nephrotoxicity, cisplatin can be used in patients with severe antenatal Bartter syndrome if required for therapy of malignancy.
机译:一名在婴儿期被诊断和治疗的患有严重的产前Bartter综合征的30岁男子患了睾丸癌。尽管已知有顺铂的肾脏并发症,但该药由于其优越的抗肿瘤作用而被用于他的化疗。在顺铂治疗期间继续非甾体抗炎药的给药。尽管他的口服钾需要量有所增加,但在完成化疗后仍能维持肾功能。尽管有显着的肾毒性,但如果需要治疗恶性肿瘤,顺铂可用于重度产前巴特综合征的患者。

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