Late Isolated Central Nervous System Relapse from Ovarian Serous Adenocarcinoma: A Case Report and Literature Review

Tiago Biachide Castria; Sylvia Regina QuintanilhaRodrigues; Maria del Pilar EstevezDiz

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Late Isolated Central Nervous System Relapse from Ovarian Serous Adenocarcinoma: A Case Report and Literature Review

机译：卵巢浆液性腺癌的晚期孤立中枢神经系统复发：一例病例报告并文献复习

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Central nervous system involvement by ovarian serous adenocarcinoma is rare. We report a case of a 60-year-old woman that developed brain metastasis as isolated site of relapse 4.5 years after a complete resection and adjuvant chemotherapy for a stage Ic disease. She proceeded to a craniotomy with resection of the lesion and, subsequently, to a whole brain radiotherapy. Nineteen months later, she developed carcinomatous meningitis as isolated site of recurrence. Patient was submitted to intrathecal chemotherapy with methotrexate; however, she died from progressive neurologic involvement disease few weeks later.

机译：卵巢浆液性腺癌累及中枢神经系统的情况很少。我们报告了一例60岁的女性，该患者在完全切除和Ic期疾病的辅助化疗后4.5年出现脑转移，成为孤立的复发部位。她进行了开颅手术并切除了病灶，随后进行了全脑放疗。 19个月后，她患上了癌性脑膜炎，成为孤立的复发部位。患者接受甲氨蝶呤鞘内化疗;然而，几周后，她死于进行性神经系统受累疾病。

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《Case Reports in Obstetrics and Gynecology》 |2014年第2期|共5页
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Tiago Biachide Castria; Sylvia Regina QuintanilhaRodrigues; Maria del Pilar EstevezDiz;
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Late Isolated Central Nervous System Relapse from Ovarian Serous Adenocarcinoma: A Case Report and Literature Review

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