A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria

Kamran Iqbal; Kapil Bhargava; Per Stahl Skov; Sidsel Falkencrone; Clive EH Grattan

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A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria

机译：血清嗜碱性粒细胞组胺释放测定阳性是慢性自发性荨麻疹患者环孢素反应的标志物

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The electronic records of 398 patients with chronic spontaneous urticaria (CSU) who had had a serum basophil histamine release assay (BHRA) performed as a marker of functional autoantibodies were audited. The BHRA was positive in 105 patients (26.4%). Fifty eight were treated with ciclosporin because they were H1 anti-histamine unresponsive. CSU patients with a positive BHRA were more likely to respond clinically (P

机译：审核了398例慢性自发性荨麻疹（CSU）患者的电子记录，这些患者进行了血清嗜碱性粒细胞组胺释放测定（BHRA）作为功能性自身抗体的标志物。 105例患者中BHRA阳性（26.4％）。 58例接受环孢素治疗，因为它们对H1抗组胺药无反应。 BHRA阳性的CSU患者更有可能在临床上做出反应（P

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《Clinical and Translational Allergy》 |2012年第1期|共页
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Kamran Iqbal; Kapil Bhargava; Per Stahl Skov; Sidsel Falkencrone; Clive EH Grattan;
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中图分类过敏性疾病;
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1. Upregulated expression of substance P in basophils of the patients with chronic spontaneous urticaria: induction of histamine release and basophil accumulation by substance P [J] . Zheng Wenjiao, Wang Junling, Zhu Wei, Cell Biology and Toxicology . 2016,第3期

机译：慢性自发性荨麻疹患者嗜碱性粒细胞中P物质的表达上调：P物质诱导组胺释放和嗜碱性粒细胞积累
2. Basophil histamine release assay predicts response and time of response to omalizumab in severe chronic spontaneous urticaria [J] . Ue Kok Loong, Bintcliffe Keyna, Gilkes Siobhan, Clinical and experimental allergy : . 2017,第12期

机译：嗜碱性组胺释放测定预测严重慢性自发性荨麻疹的奥拉米拉布对奥拉米拉的反应和时间
3. Basophil histamine release in patients with chronic spontaneous urticaria: Optimize or minimize Reply [J] . MacGlashan Donald Jr. The Journal of Allergy and Clinical Immunology . 2019,第2期

机译：慢性自发性荨麻疹患者的嗜碱性粒细胞组胺释放：优化或最小化回复
4. Laser 3D-modeling of the image of the LYVE-1 marker expression in skin lymphatic vessels and prelymphatics in patients with urticaria pigmentosa [C] . Svetlana Viktorovna Michurina, Svechnikova Natalia Nikolaevna, Andrey Yurievich Letyagin, Conference on Cognitive Sciences, Genomics and Bioinformatics . 2020

机译：色素性荨麻疹患者皮肤淋巴管和前淋巴管中LYVE-1标记表达图像的激光3D建模
5. A Unique Perspective on Automaticity: From Theory to Application in the Management of Chronic Spontaneous Urticaria [D] . Oksenhendler, Rebecca Mina. 2015

机译：自动化的独特视角：从理论到慢性自发性荨麻疹的应用
6. A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria [O] . Kamran Iqbal, Kapil Bhargava, Per Stahl Skov, 2012

机译：血清嗜碱性粒细胞组胺释放测定阳性是慢性自发性荨麻疹患者环孢素反应的标志物
7. A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria [O] . Kamran Iqbal, Kapil Bhargava, Per Skov, 2012

机译：血清嗜碱性粒细胞组胺释放测定阳性是慢性自发性荨麻疹患者环孢素反应的标志物
8. Mechanism of Histamine Release from Human Basophils [R] . Dembo, M., Goldstein, B. 1978

机译：人嗜碱性粒细胞释放组胺的机制

A positive serum basophil histamine release assay is a marker for ciclosporin-responsiveness in patients with chronic spontaneous urticaria

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