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Endothelial keratoplasty with infant donor tissue

机译：婴儿供体组织内皮角膜移植术

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Abstract: Here we report a case of endothelial keratoplasty with infant donor tissue obtained after brain death. A 52-year-old man with endothelial dysfunction of unknown cause in the right eye underwent non-Descemet stripping automated endothelial keratoplasty (nDSAEK) with tissue from an infant donor (2?years). Intraoperative and postoperative complications were recorded. Best corrected visual acuity and donor central endothelial cell density were recorded preoperatively and postoperatively. Infant donor tissue preparation with a microkeratome set at 300?μm was successful; the donor tissue was extremely elastic and soft compared with adult tissue. The central endothelial cell density of the infant donor tissue was as high as 4,291 cells/mm2. No complications were observed during donor tissue (8.0?mm in diameter) insertion with the double-glide technique (Busin glide with intraocular lens sheet glide) or any of the other procedures. Best corrected visual acuity improved from 1.7?logMAR (logarithm of the minimum angle of resolution; 0.02?decimal visual acuity) preoperatively to 0.2?logMAR (0.6) after 6?months and 0.1?logMAR (0.8) after 1 year. The central endothelial cell density after 6?months was 4,098?cells/mm2?(representing a 4.5% cell loss from preoperative donor cell measurements), and the central endothelial cell density after 1 year was 4,032?cells/mm2?(6.0% decrease). Infant donor tissue may be preferably used for DSAEKDASEK, since it may not be suitable for penetrating keratoplasty or Descemet membrane endothelial keratoplasty.
机译：摘要：在这里我们报道一例发生脑死亡后获得婴儿供体组织的内皮角膜移植手术。一名52岁的右眼内皮功能障碍原因不明的男子接受了来自婴儿捐赠者的组织（2年）的非Descemet剥离自动内皮角膜移植术（nDSAEK）。记录术中和术后并发症。术前和术后记录最佳矫正视力和供体中央内皮细胞密度。用300？μm的微型角膜刀制备婴儿供体组织成功。与成人组织相比，供体组织极具弹性和柔软性。婴儿供体组织的中央内皮细胞密度高达4,291细胞/ mm2。使用双滑行技术（眼睑滑行与人工晶状体滑行）或其他任何方法插入供体组织（直径8.0？mm）期间，未观察到并发症。最佳矫正视力从术前的1.7？logMAR（最小分辨角的对数; 0.02？十进制视力）提高到术后6个月后的0.2？logMAR（0.6）和一年后的0.1？logMAR（0.8）。 6个月后的中心内皮细胞密度为4,098？cells / mm2？（相当于术前供体细胞测量的4.5％细胞损失），一年后的中心内皮细胞密度为4,032？cells / mm2？（下降6.0％）。 ）。婴儿供体组织可能优选用于DSAEK / nDASEK，因为它可能不适合穿透性角膜移植术或Descemet膜内皮角膜移植术。

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