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首页> 外文期刊>Clinics >Septic pulmonary embolism caused by a Klebsiella pneumoniae liver abscess: clinical characteristics, imaging findings, and clinical courses
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Septic pulmonary embolism caused by a Klebsiella pneumoniae liver abscess: clinical characteristics, imaging findings, and clinical courses

机译：肺炎克雷伯菌引起的脓毒性肺栓塞：临床特征，影像学表现和临床过程

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OBJECTIVES: Septic pulmonary embolism caused by a Klebsiella (K.) pneumoniae liver abscess is rare but can cause considerable morbidity and mortality. However, clinical information regarding this condition is limited. This study was conducted to elucidate the full disease spectrum to improve its diagnosis and treatment. METHOD: We reviewed the clinical characteristics, imaging findings, and clinical courses of 14 patients diagnosed with septic pulmonary embolism caused by a K. pneumoniae liver abscess over a period of 9 years. RESULTS: The two most prevalent symptoms were fever and shortness of breath. Computed tomography findings included a feeding vessel sign (79%), nodules with or without cavities (79%), pleural effusions (71%), peripheral wedge-shaped opacities (64%), patchy ground-glass opacities (50%), air bronchograms within a nodule (36%), consolidations (21%), halo signs (14%), and lung abscesses (14%). Nine (64%) of the patients developed severe complications and required intensive care. According to follow-up chest radiography, the infiltrates and consolidations were resolved within two weeks, and the nodular opacities were resolved within one month. Two (14%) patients died of septic shock; one patient had metastatic meningitis, and the other had metastatic pericarditis. CONCLUSION: The clinical presentations ranged from insidious illness with fever and respiratory symptoms to respiratory failure and septic shock. A broad spectrum of imaging findings, ranging from nodules to multiple consolidations, was detected. Septic pulmonary embolism caused by a K. pneumoniae liver abscess combined with the metastatic infection of other vital organs confers a poor prognosis.
机译：目的：由肺炎克雷伯菌引起的脓毒性肺栓塞很少见，但会引起较高的发病率和死亡率。但是，有关这种情况的临床信息有限。进行该研究以阐明整个疾病谱以改善其诊断和治疗。方法：我们回顾了9年内诊断为由肺炎克雷伯菌肝脓肿引起的脓毒性肺栓塞的14例患者的临床特征，影像学发现和临床过程。结果：两个最普遍的症状是发烧和呼吸急促。计算机体层摄影检查的结果包括：食管征象（79％），有或无洞的结节（79％），胸腔积液（71％），周围楔形混浊（64％），片状磨玻璃混浊（50％），结节内的空气支气管造影（36％），结扎（21％），晕轮征（14％）和肺脓肿（14％）。 9名（64％）患者出现了严重的并发症，需要重症监护。根据胸部X线检查，浸润和巩固在两周内得到解决，结节混浊在一个月内得到解决。 2名（14％）患者死于败血性休克;一名患者患有转移性脑膜炎，另一名患者患有转移性心包炎。结论：临床表现范围从发烧和呼吸道症状的隐匿性疾病到呼吸衰竭和败血性休克。检测到了广泛的影像学发现，从结节到多次合并。由肺炎克雷伯菌肝脓肿引起的脓毒性肺栓塞与其他重要器官的转移性感染相结合，预后不良。

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