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首页> 外文期刊>Clinics >A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval
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A comparison of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion for oocyte retrieval

机译：异丙酚输注靶控丙泊酚过程中三种不同靶控瑞芬太尼输注速率的比较

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OBJECTIVE: To evaluate the effects of three different target-controlled remifentanil infusion rates during target-controlled propofol infusion on hemodynamic parameters, pain, sedation, and recovery score during oocyte retrieval. METHODS: Sixty-nine women were scheduled for oocyte retrieval. Target-controlled propofol infusion at an effectsite concentration of 1.5 μg/mL was instituted. The patients were randomly allocated to receive remifentanil at an effect-site concentration of either 1.5 (group I, n = 23), 2 (group II, n = 23) or 2.5 ng/mL (group III, n = 23). Hemodynamic variables, sedation, pain, the Aldrete recovery score, and side effects were recorded. RESULTS: Hemodynamic variables, sedation and pain scores and the number of patients with the maximum Aldrete recovery score 10 min after the procedure were comparable among the groups. The number of patients in group III with the maximum Aldrete recovery score 5 min after the procedure was significantly lower than that in groups I and II. One patient in group II and one patient in group III suffered from nausea. CONCLUSION: Similar pain-free conscious sedation conditions without significant changes in hemodynamic parameters were provided by all three protocols. However, target controlled infusion of remifentanil at 1.5 or 2 ng/mL proved superior at providing early recovery compared to 2.5 ng/mL.
机译：目的：评估靶控丙泊酚输注期间三种不同靶控瑞芬太尼输注速率对卵母细胞取回过程中血液动力学参数，疼痛，镇静和恢复评分的影响。方法：计划安排69名妇女进行卵母细胞取出。建立了效应浓度为1.5μg/ mL的靶控异丙酚输注。随机分配患者接受瑞芬太尼的作用部位浓度为1.5（I组，n = 23），2（II组，n = 23）或2.5 ng / mL（III组，n = 23）。记录血流动力学变量，镇静，疼痛，Aldrete恢复评分和副作用。结果：各组之间的血液动力学变量，镇静和疼痛评分以及术后10分钟Aldrete最高恢复评分的患者人数相当。手术后5分钟，Aldrete恢复评分最高的III组患者人数明显低于I和II组。第二组的一名患者和第三组的一名患者患有恶心。结论：所有三种方案均提供了类似的无痛自觉镇静条件，但血液动力学参数没有明显变化。然而，与2.5 ng / mL相比，以1.5或2 ng / mL的瑞芬太尼进行靶控输注被证明在早期恢复方面具有优势。

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